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Reduced bleeding risk with asundexian compared to apixaban in patients with atrial fibrillation
1. Asundexian 50 mg resulted in a lower rate of bleeding compared to apixaban 5 mg twice daily. 2. The ...
Tag: direct oral anticoagulant (DOAC)
Rivaroxaban prophylaxis improves clinical outcomes in high-risk patients hospitalized with COVID-19
1. The primary efficacy outcome of symptomatic and asymptomatic venous thromboembolism was significantly lower in the rivaroxaban group (3.14%) compared ...
Rivaroxaban superior to aspirin at reducing recurrent stroke in patients with embolic stroke of undetermined source and left ventricular dysfunction: (NAVIGATE ESUS Trial)
1. Rivaroxaban was superior to aspirin in reducing recurrent stroke or systemic embolism among patients with recent embolic stroke of ...
Aspirin treatment without indication in patients on direct oral anticoagulants may increase the risk of bleeding events
1. In patients treated with direct oral anticoagulants (DOACs) for atrial fibrillation or venous thromboembolism (VTE), adding aspirin (ASA) was ...
Direct oral anticoagulants more effective in patients with valvular atrial fibrillation
1. Patients who received a direct oral anticoagulant had a lower risk of thromboembolic events and major bleeds compared to ...
Low dose edoxaban prevents stroke in elderly patients with atrial fibrillation
1. Low dose edoxaban was superior to placebo in preventing stroke or systemic embolism for very elderly patients with nonvalvular ...
#VisualAbstract: Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome
1. In this randomized study comparing the efficacy of rivaroxaban with warfarin, dose-adjusted rivaroxaban treatment resulted in near doubling of ...
Rivaroxaban potentially inferior to vitamin K antagonists for treatment of thrombotic antiphospholipid antibody syndrome
1. In this randomized study comparing the efficacy of rivaroxaban with warfarin, dose-adjusted rivaroxaban treatment resulted in near doubling of ...
Peri-operative interruption of DOACs associated with low rates of bleeding and thrombosis
1. The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) cohort study evaluated the safety of standardized perioperative interruption of direct ...
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