Zorevunersen appears safe and may alleviate symptoms in children with Dravet syndrome
1. In this phase 1/2a trial involving patients with Dravet syndrome who received intrathecal zorevunersen, treatment-related adverse events occurred in ...
Tag: epilepsy
Deep-learning models displayed expert-level accuracy in detecting epileptiform discharges on electroencephalogram (EEG) recordings
1. Li and colleagues developed a deep-learning model to analyze EEG recordings and detect event-level EEG spikes. 2. The model ...
A novel validated, imaging-based risk model may predict poststroke epilepsy more accurately than existing tools
1. The IsCHEMiA score is a validated, imaging-based risk model that more accurately predicts poststroke epilepsy than existing tools across ...
Antiseizure medications do not reduce the risk of epilepsy in patients with brain abscess
1. In patients with a brain abscess, use of antiseizure medications (ASM) was not associated with a statistical difference in ...
New-generation antiseizure medications are better tolerated for patients with epilepsy
1. Newer-generation antiseizure medications (ASMs) were better tolerated and more likely to be maintained than older ASMs. 2. Only 23% ...
Praxis Precision’s relutrigine reduces seizures in rare epileptic disorders in phase 2 clinical trials
Relutrigine resulted in a 46% reduction in seizures and seizure freedom in 30% of patients. Patients also experienced meaningful improvements ...
Dietary interventions effective in treating pediatric drug-resistant epilepsy
1. In a systematic review and meta-analyses of dietary interventions for drug-resistant epilepsy in children, the ketogenic diet, modified Atkins diet, ...
Angiotensin receptor blockers may reduce the incidence of epilepsy in patients with hypertension
1. Amongst a cohort of individuals with arterial hypertension, those who were taking angiotensin receptor blocker antihypertensives had the lowest ...
Prenatal exposure to high-dose folic acid associated with increased cancer risk in children of mothers with epilepsy
1. The risk of cancer was higher amongst children of mothers with epilepsy who were exposed to high-dose folic acid ...
New prognostication tool predicts neurological deficits and long-term survival in patients with status epilepticus
1. In this retrospective cohort study, among 261 patients with status epilepticus, age, duration, and nonconvlusive status epilepticus in coma ...
