Tag: fibrinogen

1. Ziltivekimab lowered high-sensitivity CRP levels, a predictor of vascular events, compared to placebo in a dose-dependent manner. 2. Thrombotic biomarkers including fibrinogen, serum amyloid A, haptoglobin, secretory phospholipase A2, and lipoprotein were lower in treatment groups compared to placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Prior studies, including the landmark...
1. The use of fibrinogen concentrate for fibrinogen replacement, post cardiac surgery, is noninferior to cryoprecipitate. Evidence Rating Level: 1 (Excellent) Study Rundown: A common postoperative complication with cardiac surgery is excessive bleeding which consequently requires blood component transfusion.  The guidelines for the management of cardiac surgery-associated bleeding presenting with acquired hypofibrinogenemia recommend...
1. The use of fibrinogen concentrate for fibrinogen replacement, post cardiac surgery, is noninferior to cryoprecipitate. Evidence Rating Level: 1 (Excellent) Study Rundown: A common postoperative complication with cardiac surgery is excessive bleeding which consequently requires blood component transfusion.  The guidelines for the management of cardiac surgery-associated bleeding presenting with acquired...