Tag: fracture risk

1. Delayed subsequent denosumab doses were shown to increase the risk for vertebral fractures compared to on-time injection. 2. There was insufficient evidence to determine if with delayed dosing, fracture risk at other locations would be increased. Evidence Rating Level: 2 (Good) Study Rundown: Denosumab, a monoclonal antibody that inhibits the RANK...
1. Direct oral anticoagulants, specifically apixaban, were associated with lower risk of fracture in patients with atrial fibrillation compared to warfarin. Evidence Rating Level: 2 (Good) Warfarin is commonly used to prevent cardioembolic events in individuals with atrial fibrillation (AF). The impact of warfarin treatment on bone health is clinically...
Association of Anticoagulant Therapy With Risk of Fracture Among Patients With Atrial Fibrillation 1. Direct oral anticoagulants, specifically apixaban, were associated with lower risk of fracture in patients with atrial fibrillation compared to warfarin. Evidence Rating Level: 2 (Good) Warfarin is commonly used to prevent cardioembolic events in individuals with atrial fibrillation...
Association between incidence exposure to benzodiazepines in early pregnancy and risk of spontaneous abortion Previous studies have shown that benzodiazepine use in early pregnancy is associated with spontaneous abortion (SA). The association between specific benzodiazepines and the risk of SA, however, has not been investigated. In this nested case-control study...