Tag: hba1c

1. Tirzepatide was superior to placebo with regard to changes in HbA1c, serum glucose, body weight loss, and proportion of patients achieving HbA1c targets of less than 7.0%. 2. Compared to placebo, the proportion of adverse events with tirzepatide were mildly elevated. Evidence Rating Level: 1 (Excellent) Study Rundown: In many patients...
1. Time in range after 6 months was higher with rtCGM than with isCGM. 2. Participants on rtCGM scored better on the satisfaction subscale of the Diabetes Treatment Satisfaction Questionnaire status (mean difference of 2.34 points). Evidence Rating Level: 1 (Excellent) Study Rundown: Progress in the field of home glucose monitoring systems...
1. Change in mean bodyweight was -9.6% with semaglutide 2.4 mg vs. -3.4% with placebo. 2. Approximately two-thirds of patients on semaglutide 2.4 mg achieved a target HbA1c of 6.5% or less.  Evidence Rating Level: 1 (Excellent) Study Rundown: There is strong overlap between weight gain and type 2 diabetes, with the...
1. 10-year remission rates were significantly higher for Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD) than medical therapy. 2. Patients in the BPD and RYGB groups had fewer diabetes-related complications.  Evidence Rating Level: 1 (Excellent) Study Rundown: Compared to conventional therapy, metabolic surgery results in significant short-term improvements among patients with...
1. Participants using the novel advanced hybrid insulin delivery system (Medtronic) had a greater proportion of time spent in their target glucose range versus control. 2. Proportion of time spent in hypoglycemic ranges was non-inferior between the Medtronic and control groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Although various technological advances...
1. The closed-loop system maintained glucose levels within the target range for a significantly greater percentage of time for children with type 1 diabetes. 2. More adverse events were reported with use of the closed-loop system. Evidence Rating Level: 1 (Excellent) Study Rundown: The target glycated hemoglobin level is difficult to maintain...
Multiple daily injections (MDI) and continuous subcutaneous insulin infusion (CSII) are two forms of intensive insulin regimens utilized by patients with type 1 diabetes. Here, MDI and CSII are compared in terms of their safety, efficacy, and cost in the first year after a diagnosis of type 1 diabetes....
1. Mean glucose concentration was significantly lower in black compared to white patients; however, HbA1c levels in black patients were higher than white patients. 2. Differences in glucose concentration with HbA1c may be attributed to racial differences in glycation of hemoglobin. Evidence Rating Level: 2 (Good) Study Rundown: Hemoglobin A1c (HbA1c) is...
1. The combination of insulin degludec and the GLP1 antagonist, liraglutide, lowered the HbA1c in patients with type II diabetes to a greater extent than up-titration of insulin glargine. 2. Degludec/liraglutide was also associated with less adverse effects, including frequency of hypoglycemic episodes, weight gain, self-reported physical functioning, and overall...
Image: CC/Wiki 1. At 6 months, nonsurgical therapy of periodontitis was not shown to improve HbA1c  levels in type II diabetes patients.  2. Although non-surgical periodontal treatment did improve clinical measures of chronic periodontitis, it is not recommended as method to improve glycemic control in diabetes patients.  Evidence Rating Level: 1 (Excellent)  Study Rundown:...