Tag: heart attack

1. Compared to healthy matched controls, individuals with multiple sclerosis demonstrated significantly increased risk of cerebrovascular disease, acute coronary syndrome, cardiovascular disease-related mortality, and all-cause mortality. Evidence Rating Level: 2 (Good) Multiple sclerosis (MS) is an autoimmune disease characterized by the demyelination of nerve fibers in the central nervous system, resulting in...
1. In patients with STEMI and multivessel coronary artery disease, those randomized to the complete revascularization group experienced lower rates of cardiovascular death or myocardial infarction (MI) at 3 years compared to patients who were randomized to the culprit-lesion-only percutaneous coronary intervention group. 2. Both groups experienced similar rates of...
1. The incidence and mortality associated with cardiovascular disease has decreased over a generation in a Native American cohort, however, improvements in age-specific mortality amongst females has not been consistently demonstrated Evidence Rating Level: 2 (Good) High morbidity and mortality rates owing to cardiovascular disease (CVD) have been observed in...
1. In patients with STEMI and multivessel coronary artery disease, those randomized to the complete revascularization group experienced lower rates of cardiovascular death or myocardial infarction (MI) at 3 years compared to patients who were randomized to the culprit-lesion-only percutaneous coronary intervention group. 2. Both groups experienced similar rates of...
1. Near-infrared spectroscopy imaging in patients undergoing cardiac catheterization for suspected coronary artery disease can be used in identifying high-risk non-culprit lesions contributing to future major adverse coronary events.  Evidence Rating Level: 2 (Good) Coronary artery disease is the leading cause of death worldwide. While modifiable risk factors are the target...
The risk of adverse cardiovascular outcomes in patients hospitalized with acute coronary syndrome (ACS) is highest in elderly patients. Although recent clinical trials have shown that high-intensity statin therapy significantly reduces adverse cardiovascular events for patients with established coronary heart disease, its use in elderly individuals remains controversial. As...
1. In this retrospective cohort study of adults under age 50 with myocardial infarction, 9% met criteria for definite or probable familial hypercholesterolemia, which is roughly 20x the prevalence in the general American population. 2. Only about two-thirds of patients with familial hypercholesterolemia and myocardial infarction were discharged on high...
The following study summary is an excerpt from the book 2 Minute Medicine’s The Classics in Radiology: Summaries of Clinically Relevant & Recent Landmark Studies, 1e (The Classics Series). 1. In patients presenting to the emergency department with acute chest pain, evaluation with computed tomographic coronary angiography (CTCA) led to significantly...
1. Among patients that suffered a recent acute coronary syndrome (ACS) and had elevated levels of atherogenic lipoproteins despite intensive or maximum-intensive statin therapy, alirocumab reduced the number of recurrent cardiovascular ischemic events. This response was more robust with higher levels of low-density lipoprotein (LDL) cholesterol. 2. The safety profile...
Image: CC/L. academia 1. Treating patients with captopril after acute MI with asymptomatic LV dysfunction reduces mortality from cardiovascular causes (i.e., atherosclerotic heart disease, progressive heart failure). 2. The captopril group experienced lower rates of hospitalization due to heart failure and recurrent MI. Study Rundown: The SAVE trial was the first to demonstrate...