Alirocumab linked to significant and sustained reduction in LDL cholesterol [ODYSSEY LONG TERM]
1. In patients on maximal statin treatment and with LDL levels over 70mg/dL, the addition of alirocumab reduced LDL levels ...
Tag: LDL
Evolocumab plus standard therapy reduces LDL, cardiovascular events compared to standard anti-cholesterol therapy alone [OSLER-1 & OSLER-2 Trials]
1. Compared to those treated with only standard therapy, patients treated with the addition of evolocumab, a monoclonal antibody that ...
Key mutations may protect against coronary artery disease
1. Genetic mutations that led to the inactivation NPC1L1, a lipid transporter protein, were linked to lower low-density lipoprotein (LDL) ...
Patient lacking apolipoprotein E has altered lipid metabolism without neurocognitive or visual defects
1. Complete lack of endogenous Apolipoprotein E (apoE) was associated with altered lipid metabolism, including high cholesterol. 2. Lack of ...