1. In this observational cohort study, the rates of 21-day survival for patients with acute liver failure have gradually increased since 1998.
2. During this time period, the causes of acute liver failure and the demographics of patients presenting with this condition have remained relatively constant.
Evidence Rating Level: 2 (Good)
1. Compared to placebo, treating patients with severe alcoholic hepatitis with 28 days of prednisolone significantly improved the short-term survival up to 6 months.
2. There remains significant controversy surrounding the use of glucocorticoids in managing severe alcoholic hepatitis, as numerous other trials have demonstrated no mortality benefit, but significantly...
1. The Model for End-Stage Liver Disease (MELD) is a reliable tool for predicting short-term survival in patients with advanced liver disease
2. The score is generalizable to diverse etiologies and a wide range of disease severity
Original Date of Publication: February 2001
Study Rundown: The Model for End-Stage Liver Disease (MELD)...