Tag: osteoarthritis

1. This study found no difference in reported pain levels among patients with knee osteoarthritis who took wither placebo or 50,000 IU of vitamin D3 per week for 24 months. 2. This study found no difference in tibial cartilage thickness among patients with knee osteoarthritis who took wither placebo or...
1. From a randomized clinical trial, intervention at both the patient and provider level showed modest improvement in osteoarthritis management of patient function and physical activity when compared to control subjects. 2. Depressive symptoms, BMI, and pain scores of patients were not significantly affected by interventional methods. Evidence Rating Level: 1...
1. In a meta-analysis of 14 prospective studies, increased body mass index (BMI) was a significant risk factor for knee osteoarthritis (OA). 2. BMI was found to be an independent predictor of knee OA, regardless of gender, sex, age, country, or duration of follow-up. Evidence Rating Level: 2 (Good)  ...
1. From a systematic review, intra-articular and topical placebos had greater effects on pain scores than oral placebos. 2. When accounting for differential effects of placebo treatments, intra-articular hyaluronic acid controlled pain best at 3 months. Evidence Rating Level: 1 (Excellent) Study Rundown: Placebo treatments are used as inactive treatments to establish...
1. There was no significant difference in pain scores between groups that received corticosteroid intra-articular injections with exercise therapy and those who received placebo injections and exercise therapy. Evidence Rating Level: 1 (Excellent) Study Rundown: Osteoarthritis (OA) is a common and debilitating form of arthritis that may limit mobility...
1. Intra-articular hyaluronic acid injections were superior to some oral NSAIDs for treatment of knee osteoarthritis pain. 2. Of all interventions studied, only celecoxib was not superior to acetaminophen for treatment of knee osteoarthritis pain. Evidence Rating Level: 1 (Excellent) Study Rundown: Knee osteoarthritis (OA) is a highly prevalent disease, especially among...
Originally published by Harvard Health. What Is It? Inside a joint, a tissue called cartilage cushions the joint and prevents the bones from rubbing against each other. Osteoarthritis occurs when the cartilage of a joint erodes (breaks down). Bones begin to rub against each other, causing pain and difficulty moving the joint....
Image: PD  1. There was no significant difference in patient-reported outcomes after 12 weeks of physical therapy versus 12 weeks of placebo physical therapy for hip osteoarthritis.  2. Participants in the both the physical therapy and placebo physical therapy groups reported a statistically significant decrease in hip osteoarthritis pain and increase...
Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing Clostridium difficile is responsible for diarrhea and colitis in many patients undergoing antibiotic treatment. Many healthcare facilities have protocols for isolation and...
Image: PD  1. Lateral wedges are no more efficacious than neutral wedges at reducing knee pain associated with medial knee osteoarthritis. 2. Lateral wedge insoles show a moderate association with decreased pain when compared to not using an insole.  Evidence Rating Level: 1 (Excellent)  Study Rundown: Osteoarthritis of the knee is a painful...