Tag: Parkinson Disease

1. Pimavanserin was shown to lead to a lower risk of relapse of psychosis in patients who had an initial response to pimavanserin for dementia-related psychosis.   2. The trial was stopped early for efficacy. Evidence Rating Level: 1 (Excellent) Study Rundown: Dementia-related psychosis results in behavioral disturbances, decreased quality of life,...
1. Among patients receiving deep brain stimulation for Parkinson’s disease, a home health management program was found to be safe, feasible, and significantly reduced the need for traditional clinic management. Evidence Rating Level: 1 (Excellent) Study Rundown: Deep brain stimulation (DBS) has shown to be effective in the management of...
1. In patients suffering from Parkinson’s disease displaying signs of motor dysfunction even after receiving treatment, this randomized control trial revealed improvement in motor features, such as tremor and rigidity, following focused ultrasound subthalamotomy when compared to those that received a sham procedure. 2. This trial displayed adverse events in...
1. Two novel gene loci among Asian populations were identified and associated with Parkinson disease (SV2C, WBSCR17) that had not been previously included in European loci or polygenic risk score models. Evidence Rating Level: 2 (Good) Parkinson disease (PD) is a leading age-related neurodegenerative disease and cause of death, resulting...
Viral Load Dynamics and Disease Severity In Patients Infected With SARS-CoV-2 In Zhejiang Province, China, January-March 2020: Retrospective Cohort Study 1. Stool samples demonstrated significantly longer duration of positive viral load than both respiratory and serum samples. 2. Length of positive RNA detection was associated with disease duration with a peak...