Tag: pediatric

1. In recent years, the risk of persistent disability has been significantly reduced in patients with pediatric-onset multiple sclerosis (POMS), likely owing to availability of new disease-modifying therapies (DMTs) and changes to therapeutic paradigms over time. 2. Further research in therapeutic efficacy and management in the pediatric population is needed...

1. Pediatric patients during the COVID-19 pandemic present with a wide range of cardiac manifestations that require early detection and treatment. Evidence Rating Level: 2 (Good) The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has resulted in increased hyperinflammatory presentations in otherwise healthy children. This international, multi-center, retrospective chart...

1. Selective serotonin reuptake inhibitor use among children and adolescents with public health insurance was found to be associated with a mildly increased risk for the developed of type 2 diabetes mellitus. 2. The magnitude of this risk, overall, was substantially lower than that of other risk factors for the...

1. Among trauma patients aged 10 to 17, the use of low molecular weight heparin as compared with unfractionated heparin was associated with fewer episodes of venous thromboembolism as well as a reduction in mortality. Evidence Level Rating: 2 (Good) Low molecular weight heparin (LMWH) and unfractionated heparin (UFH) are the...

1. Metformin was found to be safe and tolerable in survivors of pediatric brain tumors. 2. Metformin was associated with retention of memory and processing speed abilities, as well as a reduction of white matter loss. Evidence Rating Level: 1 (Excellent) It is believed that endogenous neural precursor cells (NPCs) can promote...

Neonatal intensive care unit (NICU) medical staff who were exposed to maternal expressions of gratitude had higher scores in procedural and therapeutic planning and prosocial behaviors in response to neonatal medical emergency scenarios when compared to medical staff who were exposed to neutral maternal statements. Evidence Rating: Level 1...

1. While overall prescribing of medications decreased compared to the early 2000s, the use of ADHD medication, asthma medicine, and contraceptive use increased while use of antibiotics, antihistamines, and upper respiratory combination medications decreased. 2. Most commonly used medication classes include asthma medications, antibiotics, ADHD medications, topical agents, and antihistamines. ...

1. In this prospective cohort, adolescents with type II diabetes (DM2) were more predisposed to almost every diabetes related complication at age 21 than those with type I diabetes (DM1). 2. When controlling for known risk factors, such as obesity and glycemic control, those with DM2 still had a higher...

1. The study demonstrated that in critically ill pediatric patients, there was no significant difference in total number of ICU-free days up to day 28 between lower- and higher-target glucose groups. 2. The study was stopped early due to the low likelihood of benefit for patients. Evidence Rating Level: 1 (Excellent) Study...

1. Periviable infants born from 2008-2011 survived to 18-22 months corrected age at a higher rate than those born from 2000-2003. 2. Rates of reaching 18-22 months corrected age without neurodevelopmental impairment were higher for periviable infants born during 2008-2011 compared to those born from 2000-2003. Evidence Rating: 2 (Good) Study Rundown:...