Tag: preterm birth

1. Systematic review of RCTs demonstrates reduced rate of early preterm birth (<34 weeks) for high-risk (previous spontaneous preterm birth, short cervix) singleton pregnancies with vaginal progesterone and intramuscular 17-hydroxyprogesterone caproate (17-OHPC). 2. Efficacy of vaginal progesterone and 17-OHPC may be more effective for women with short cervices.  Evidence Rating Level:...

1. Rate of treatment failure within 7 days of extubation was higher in patients that received post-extubation high-flow nasal cannula (HFNC), as compared to those that received nasal intermittent positive pressure ventilation (NIPPV) or nasal continuous positive airway pressure (NCPAP). 2. Histologic chorioamnionitis, treated patent ductus arteriosus (PDA), and younger...

1. In this randomized controlled trial involving extremely preterm infants, high dose erythropoietin did not reduce the risk of death or severe neurodevelopmental impairment at two years of age versus placebo. 2. This finding contradicts the results of previous studies involving different dosing regimens and more mature babies. Evidence Rating Level: 1...

1. In this randomized controlled trial involving extremely preterm infants, high dose erythropoietin did not reduce the risk of death or severe neurodevelopmental impairment at two years of age versus placebo. 2. This finding contradicts the results of previous studies involving different dosing regimens and more mature babies. Evidence Rating Level:...

1. A multicenter randomized control trial concluded that n-3 polyunsaturated fatty acid supplementation in pregnancy did not change the risk of preterm delivery or the risk of post-term induction or cesarean section. 2. The safety profile of n-3 polyunsaturated fatty acid supplementation in pregnancy was similar to control. Evidence Rating Level:...

1. Following the Joint Commission’s adoption of the 39-week rule to reduce early, elective deliveries, there has been a marginal significant increase in the stillbirth rate while overall mortality rates have remained relatively stable. Evidence Rating Level: 2 (Good) Studies on the association of mortality with the adoption of the Joint Commission’s...

1. A multicenter randomized control trial concluded that n-3 polyunsaturated fatty acid supplementation in pregnancy did not change the risk of preterm delivery or the risk of post-term induction or cesarean section. 2. The safety profile of n-3 polyunsaturated fatty acid supplementation in pregnancy was similar to control. Evidence Rating...

Gender differences in Twitter use and influence among health policy and health services researchers 1. Women’s voices on common social media platforms appear less influential and have less reach than their male counterparts in the health policy and health service research arena, suggesting that social media may re-enforce known gender...

Preeclampsia is associated with increased morbidity and mortality for both mother and infant. In addition to maternal and fetal assessment, timely delivery after 37 weeks’ gestation is recommended to minimize maternal and perinatal morbidity. In women with late preterm preeclampsia, between 34 and 37 weeks’ gestation, however, there is...

Preterm birth is the leading cause of infant mortality and neonatal morbidity. Maternal obesity is associated with an increased risk of gestational diabetes and hypertensive disorders of pregnancy, which can, in turn, contribute to medically indicated preterm birth. As such, pre-pregnancy obesity represents a potentially modifiable risk factor for...