Tag: preterm birth

Preterm birth is the leading cause of infant mortality and neonatal morbidity. Maternal obesity is associated with an increased risk of gestational diabetes and hypertensive disorders of pregnancy, which can, in turn, contribute to medically indicated preterm birth. As such, pre-pregnancy obesity represents a potentially modifiable risk factor for...
Efficacy of prehospital criteria in identifying trauma patients susceptible to undertriage While the early recognition of severe traumatic injury is associated with improved morbidity and mortality, undertriage has been associated with poorer patient outcomes. Previous research has shown that tachypnea and blunt thoracic injury are associated with undertriage. In this...
Fetal nephrogenesis is most significant in the third trimester of pregnancy, and is interrupted by preterm birth before 37 weeks of gestation, resulting in lower nephron numbers and the development of hypertension and progressive renal disease later in life. While low birth weight has been associated with chronic kidney...
Preterm birth remains a leading cause of lifelong neurodevelopmental disability. While the effect of brain injury on neurodevelopmental disability has been studied extensively, far less is known with respect to the role of environments and experiences in moderating these associations. In this prospective cohort study, preterm neonates (24-32 weeks’...
Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study Early evidence has suggested a strong association between HIV viral load and the risk of transmission to an HIV-negative partner, as well...
1. State Medicaid expansion was not associated with differences in overall rates of low birth weight or preterm birth outcomes. 2. There were improvements in relative disparities for black infants compared with white infants among the states that expanded versus the states that did not. Evidence Rating Level: 2 (Good) Study Rundown:...
1. Within a cohort of infants born extremely preterm (EPT), there were elevated rates of high systolic blood pressure (SBP≥90%ile) and hypertension (SBP≥95%ile) when these children reached school age. 2. School age children with high SBP who were born EPT, were significantly more likely to have been born to mothers...
1. The combination of poverty and preterm birth had additive negative effects on later cognitive function. 2. Poverty alone was associated with worse cognitive outcomes than preterm birth alone. Evidence Rating Level: 2 (Good) Study Rundown: Though poverty and preterm birth have each been independently associated with negative cognitive outcomes for children,...
1. The rate and risk of mortality <28 days from birth was the highest in infants born with both preterm birth (PTB) and small for gestational age (SGA) status, followed by those born with PTB without SGA, then term birth (TB) with SGA (TB-SGA) and TB without SGA. 2....
1. The birth prevalence of Hirschsprung disease (HSCR) from 1987 to 2012 in Sweden was found to be steady at approximately 1 in 5000 with a male predominance. 2. Significantly more babies with HSCR were born prematurely compared to healthy controls and data suggested maternal obesity as a risk indicator. Evidence...