Tag: probiotics

1. The administration of the probiotic Lactobacillus rhamnosus GG resulted in no significant difference compared to placebo in the development of ventilator-associated pneumonia in critically ill patients requiring mechanical ventilation. 2. The findings do not support the use of Lactobacillus rhamnosus GG for the prevention of ventilator-associated pneumonia or other...

1. Overall mortality, NEC morbidity, sepsis morbidity, time to enteral feeding, and length of hospital stay were decreased in premature infants receiving any two of Lactobacillus, Bifidobacterium, and prebiotic. 2. Use of a single probiotic was inferior to using combinations of probiotics or a probiotic plus a prebiotic. Evidence Rating Level:...

The use of probiotics has been suggested as a way to improve outcomes in children with gastroenteritis. In this randomized controlled trial, investigators randomized 886 children age 3 to 48 months of age with gastroenteritis to receive a placebo or combination product containing Lactobacillus rhamnosus R0011 and L. helveticus...

1. Studies are often lacking or inadequate with respect to reporting adverse events (AEs) related to probiotics and prebiotics. 2. The majority of the studies in the trial did not give a specified definition for AEs or serious adverse events (SAEs). Evidence Rating Level: 1 (Excellent) Study Rundown: Prebiotics and probiotics are...

1. There were no differences in preterm delivery between women randomized to receive an 8-week oral probiotic regimen and those randomized to the control group. 2. There were no differences in vaginal microbiotic health. Evidence Rating Level: 1 (Excellent) Study Rundown: Preterm delivery (<37 weeks gestation) accounts for 75 percent of infant...

Image: CC/Wiki/Blaylock. Lactobacillus 1. Daily use of prophylactic probiotics was associated with decreased colic, regurgitation, and constipation during the first three months of life.  2. Use of prophylactic probiotics was associated with reduced overall cost for both the family and community.  Evidence Rating Level: 1 (Excellent)       Study Rundown: Findings from this multicenter double-blinded...

Image: PD  1. Investigators found that children exposed to probiotics during pregnancy or the first year of life are equally at risk for asthma, wheeze, and lower respiratory tract infections. Evidence Rating Level: 2 (Good)  Study Rundown: This meta-analysis aggregated results from 20 studies, across various countries, to evaluate the impact of...

Image: PD 1. Probiotic supplementation in very preterm infants reduced the incidence of necrotizing enterocolitis (NEC), Bell Stage 2 and greater, but not late-onset sepsis or all-cause mortality.  Number needed to treat was 43 infants to prevent 1 NEC episode. 2. No adverse effects were reported with probiotic supplementation. Evidence Rating Level:...