Tag: pulmonology

Click to read the study in CMAJ Image: PD ©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the...
Click to read the study in CMAJ 1. In patients positive for COVID-19 suffering cardiac injury, cardiac troponin (cTnI) levels were associated with poor survival, with peak cTnI levels shown to predict the need for invasive ventilation. Evidence Rating Level: 2 (Good) Reports show that patients with COVID-19-associated pneumonia and cardiac injury...
1. Expression of IFN-α is found to be lower after successful treatment of tuberculosis. Evidence Rating Level: 2 (Good) Tuberculosis (TB) is an infectious disease killing over 1 million people annually worldwide, caused by the bacterium M. tuberculosis (M.tb). The immune response to TB involves T cells that express signalling proteins...
1. Lincocin® appeared to outperform Azitro® in the treatment of pneumonia associated with Covid-19. Evidence Rating Level: 2 (Good) Although as much as 80% of patients show only minor symptoms from contracting Covid-19, complications such as pneumonia can arise from Covid-19, especially in elderly patients and individuals with chronic conditions. There...
1. Marijuana use is associated with increased cough and sputum production. 2. Limited data exists to assess the relationship between marijuana use and pulmonary function and obstructive lung disease. Evidence Rating Level: 1 (Excellent) Study Rundown: Rates of marijuana use continue to increase in the United States each year; yet, the health...
Image: PD 1. Adult clinical decision rules such as the Wells criteria and Pulmonary Embolism Rule-out Criteria (PERC) may miss pulmonary emboli (PE) when applied to the pediatric population.  2. Obesity is a known risk factor for PE, but not included in Wells criteria or PERC. Half of study patients with...
Image: PD/ Fibrotic lung 1. Ambrisentan is ineffective in delaying disease progression in idiopathic pulmonary fibrosis (IPF). 2. Compared to placebo, Ambrisentan is associated with increased risk of disease progression and respiratory hospitalization. Evidence rating level: 1 (Excellent) Study rundown: Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive form of fibrotic interstitial lung disease...
Image: PD 1. Elevated levels of CRP, fibrinogen, and leukocyte count are associated with an increased risk of COPD exacerbations over one year. 2. There was a stepwise increase in the risk of frequent exacerbations over the 1, 3, and 5 year follow-up period based upon the number of biomarkers present. Evidence...
Image: PD 1. PICC-related deep vein thrombosis occurs in 2.7% of PICC patients, with highest frequency in patients who are critically ill and those with cancer. 2. PICCs are associated with a higher rate of deep vein thrombosis than other central venous catheters (CVCs), with a pooled OR of 2.55. Evidence Rating...
Image: PD 1. Neutrophil elastase activity in bronchoalveolar lavage fluid at 3 months is a risk factor for persistent bronchiectasis at 12 months and 3 years of age.   Study Rundown: Bronchiectasis, the abnormal dilation of parts of the bronchial tree, is a clinically significant consequence of cystic fibrosis (CF). In children...