Oxygenated hypothermic perfusion reduces post-kidney transplant complications
1. Oxygenated hypothermic machine perfusion (HMPO2) of kidneys donated after circulatory death was associated with fewer severe complications and lower ...
Tag: transplant
Glucocorticoid compounds improve stem cell transplant efficiency in mice [PreClinical]
1. Following treatment with glucocorticoids, human hematopoietic stem cells (HSCs) from cord blood demonstrated enhanced homing and engraftment to ...
![Engineered stem cells mitigate liver damage caused by radiation [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2014/12/Human_embryonic_stem_cells-350x250.png)
Inhibition of the immunoproteasome may improve graft acceptance [PreClinical]
1. A targeted immunoproteasome inhibitor, DPLG3, was found to have high selectivity for the immune cell proteasome and was ...
Cord blood transplant linked to improved survival and lower relapse rate
1. Survival after allogeneic hematopoietic cell transplant was better in patients treated with cord blood than in patients treated with ...
Modified embryonic stem cells may prolong survival of surgical grafts
1. When stimulated with a variety of growth and inflammatory factors, embryonic stem cells (ESCs) took on a macrophage-like phenotype, ...
Double-unit cord-blood transplantation does not aid survival in children with hematologic malignancy
1. In children with hematologic malignancy, there was no significant difference in terms of 1-year survival between single- and double-unit ...
Donor and recipient regulatory T-cells may promote transplant tolerance in mice
1. Depletion of all Foxp3+ regulatory T-cells (Tregs) induced rejection of stable skin and heart allogeneic transplants in a hematopoietic ...
Novel mTOR inhibitor may prolong heart transplant survival in mice
1. Chemotherapy agent AZD80559, a competitive mTOR inhibitor, suppressed T cell proliferation in vitro more effectively than Rapamycin. 2. Like ...
Predictors of successful transplantation for severe combined immunodeficiency
1. Factors that predict survival after stem cell transplant for severe combined immunodeficiency (SCID) include: age less than 3.5 months, ...
Sirolimus may prevent graft failure in patients with renal transplant for antiphospholipid syndrome
1. Antiphospholipid syndrome (APLS) in an autoimmune condition causing mechanical endothelial injury leading to activation of a pathway that triggers ...
