• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home StudyGraphics

#VisualAbstract: Meningococcal B Vaccine and Meningococcal Carriage in Adolescents in Australia

byConstance Wu
February 19, 2020
in StudyGraphics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

RELATED REPORTS

Past infection with pre-omicron variants of COVID-19 protects against re-infection

Intranasal vaccine against Bordetella pertussis invokes seronegative IgA response

Regular physical activity may improve vaccine effectiveness against COVID-19 outcomes

1. In this cluster-randomized trial involving Australian adolescents, administration of 4CMenB did not result in lower prevalence of carriage of any disease-causing genogroup of N. meningitidis at 12 months.

2. While 4CMenB may decrease the likelihood of late cases in outbreaks, its ineffectiveness in reducing transmission means that antibiotics remain a necessary measure for elimination of carriage.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Meningococcal disease has a rapid progression and a high case fatality rate with the highest incidence in infants and young adults. While the relationship between asymptomatic carriage and risk of disease is not well characterized, it is hypothesized that reducing carriage prevalence in adolescents could confer some degree of indirect protection upon vulnerable persons, especially unvaccinated infants. The vaccine 4CMenB has been shown to be protective in infants and toddlers for at least two years, but its effects on carriage of disease-causing meningococci are unknown. This study found that, in secondary school students, administration of 4CMenB resulted in no significant difference in carriage prevalence at 12 months. Additionally, no between-group differences were observed in any prespecified secondary outcomes such as the prevalence of carriage of individual genogroups and acquisition of carriage. However, a number of risk factors were identified, including later year of schooling, smoking, and participation in intimate kissing. These findings are consistent with those of previous studies in which reduction of carriage occurred mostly in group Y with little effect on group B carriage. Strengths of this study were randomization at the school level, real-world design, and high retention and adherence. Some limitations were the lower-than-anticipated prevalence of carriage at 12 months and the use of a single outcome measure.

Click here to ready the study in NEJM

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: bacterial meningitismeningococcusN. meningitidisneisseriavaccine
Previous Post

Short and late sleep associated with adiposity in children

Next Post

Improvements in survival after allogeneic hematopoietic cell transplantation have continued over the past decade

RelatedReports

Decreased expression of nasal ACE2 may be correlated with lower prevalence of COVID-19 in children
Chronic Disease

Past infection with pre-omicron variants of COVID-19 protects against re-infection

March 28, 2023
Algorithm improves pediatric chronic cough outcomes
Infectious Disease

Intranasal vaccine against Bordetella pertussis invokes seronegative IgA response

March 22, 2023
Reduced gestational weight gain with lifestyle intervention
Chronic Disease

Regular physical activity may improve vaccine effectiveness against COVID-19 outcomes

November 28, 2022
Exercise improves aromatase inhibitor-induced arthralgia in breast cancer survivors
Wellness

Wellness Check: Exercise

November 24, 2022
Next Post
Severe subtype of acute lymphoblastic leukemia susceptible to FDA-approved kinase inhibitors

Improvements in survival after allogeneic hematopoietic cell transplantation have continued over the past decade

#VisualAbstract: Ubrogepant for the Treatment of Migraine

#VisualAbstract: Ubrogepant for the Treatment of Migraine

Many new pediatric asthma cases attributable to obesity

Adolescent obesity and midlife cancer risk

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • SAR-CoV-2 infection during pregnancy may lead to adverse neurodevelopmental outcomes in male offspring
  • Hyperfractionated radiotherapy reduces complication rates compared to standard fractionation for locally advanced nasopharyngeal carcinoma
  • Lebrikizumab effective in treating moderate-to-severe atopic dermatitis
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options