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SGLT2 inhibitors may delay cognitive impairment in elderly patients with heart failure
1. In elderly patients 65 years of age or older with heart failure with reduced ejection fraction (HFrEF), regular use...
Cardiology
Reports of high-impact cardiology studies by medical professionals
Mazdutide significantly reduces weight in adults with overweight or obesity
1. In this randomized controlled trial, weekly administration of Mazdutide resulted in significant weight reduction in adults classified as overweight...
Cerebral embolic protection does not decrease stroke incidence in TAVI patients
1. In this randomized trial, the use of cerebral embolic protection (CEP) did not decrease the 72-hour incidence of stroke...
Ablation may reduce stroke risk, death, heart failure hospitalization in patients with atrial fibrillation
1. In this systematic review and meta-analysis, catheter ablation was found to reduce overall risk of ischemic stroke, hospitalization for...
Novel inhibitory antibody, MAR001, lowers triglycerides and remnant cholesterol in humans
1. ANGPTL4 inhibition decreased triglyceride and remnant cholesterol levels by over 50%. 2. MAR001 was well-tolerated with no significant treatment-related...
Tirzepatide-associated improvements in cardiometabolic risk factors linked to degree of weight loss
1. In this post-hoc analysis of the SURMOUNT-1 trial, there was a mostly linear relationship between percentage change in weight...
Repeated medial branch blocks do not improve pain outcomes for thermal radiofrequency ablation
1. For patients with facet-mediated spine pain that achieve ≥80% pain relief after a medial branch block, a second diagnostic...
Artificial intelligence may assist in early detection of decreased ejection fraction on echocardiograms
1. AI-assisted electrocardiogram (ECG) improves early detection of low ejection fraction in hospitalized patients by enhancing diagnostic precision without increasing...
Transcatheter closure of patent ductus arteriosus demonstrates similar outcomes compared to surgical repair
1. Respiratory outcomes for preterm infants with a patent ductus arteriosus (PDA) undergoing transcatheter closure compared to surgical ligation did...
Obicetrapib and ezetimibe combination therapy lowers LDL cholesterol in high-risk patients
1. FDC obicetrapib plus ezetimibe significantly decreased LDL cholesterol levels by 48.6% compared to placebo. 2. Serious adverse events were...