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The Impact of Sarcopenia on Clinical Outcomes in Pediatric Crohn’s Disease
1. In children with Crohn’s disease (CD), sarcopenia at diagnosis was associated with a greater chance of relapse in the...
Gastroenterology
Reports of high-impact gastroenterology studies by medical professionals
Efruxifermin improves fibrosis in patients with metabolic dysfunction-associated steatohepatitis
1. Efruxifermin 50 mg once-weekly significantly improved fibrosis at 96 weeks versus placebo. 2. MASH resolution without worsened fibrosis was...
Computed Tomographic Angiography and Yield for Gastrointestinal Bleeding in the Emergency Department
1. Between the years 2017 and 2023, the proportion of total computed tomographic angiography (CTA) examinations related to gastrointestinal bleeding...
Long-term Outcomes of Patients with Crohn’s Disease Treated with Risankizumab
1. In adult patients with Crohn’s disease (CD) treated with risankizumab, only 13% of patients experienced treatment failure while 23%...
Association between serum albumin to creatinine ratio and non-alcoholic fatty liver disease: a longitudinal cohort study in non-obese Chinese individuals
1. In a group of Chinese patients with normal low-density lipoprotein cholesterol (LDL-c), serum albumin to creatinine (sACR) showed an...
Personalized risk messages may not increase colorectal cancer screening uptake
1. In this randomized controlled trial, using personalized risk messages and provider notifications did not significantly increase screening uptake overall....
Machine learning models diagnose celiac disease at similar performance levels to pathologists
1. Jaeckle and colleagues assessed the performance of machine learning models to diagnose celiac disease based on duodenal biopsies. 2....
Trastuzumab deruxtecan leads to longer overall survival than ramucirumab plus paclitaxel in HER2-positive gastric cancer
1. In this randomized controlled trial, among adults with HER2-positive unresectable or metastatic gastric cancer who had previously progressed on...
Ustekinumab may be superior to Vedolizumab for the treatment of Crohn’s disease
1. In patients with Crohn’s disease (CD) of the pouch following ileal-pouch anal anastomosis (IPAA) for medically-refractory ulcerative colitis (UC),...
mFOLFIRINOX may have a limited role in pancreatic cancer in Phase II/III trial
1. In patients with metastatic pancreatic cancer, neither modified fluorouracil, leucovorin, irinotecan and oxaliplatin (mFOLFIRINOX) or S-1, irinotecan and oxaliplatin...
