Nivolumab plus ipilimumab improves survival over lenvatinib or sorafenib in liver cancer
1. Median overall survival was 3.1 months greater in the nivolumab plus ipilimumab group. 2. Grade 3-4 treatment-related adverse events...
Gastroenterology
Reports of high-impact gastroenterology studies by medical professionals
Rectoscopy alone may be sufficient to evaluate for remission of ulcerative colitis
1. Rectoscopy alone for evaluation of endoscopic and histologic remission of ulcerative colitis (UC) had good accuracy and is sufficient...
Birth cohort effects observed for increased appendiceal adenocarcinoma incidence
1. In this retrospective cohort study, age-specific incidence rates of appendiceal adenocarcinoma increased by time period. 2. Local drift for...
Semaglutide improves walking ability in patients with peripheral artery disease and type 2 diabetes
1. Maximum walking distance at 52 weeks was significantly improved with semaglutide. 2. There were fewer treatment-related serious adverse events...
Both intestinal ultrasound and magnetic resonance imaging can assess radiologic stricturing in Crohn’s disease
1. Intestinal ultrasound (IUS) and magnetic resonance imaging (MRI) were effective imaging modalities for the assessment of the radiologic response...
Particulate foods not associated with incident diverticulitis in women
1. In this prospective cohort study, dietary intake of peanuts, nuts, and seeds was not associated with increased risk of...
Probiotic mitigates gut hypoperfusion-associated acute gastrointestinal injury in patients undergoing cardiopulmonary bypass
1. In this randomized controlled trial, preoperative probiotic supplementation was associated with a reduced incidence of acute gastrointestinal injury (AGI)...
Heterogeneous treatment effects of stress ulcer prophylaxis among ICU patients at risk for gastrointestinal bleeding
1. In patients admitted to the intensive care unit (ICU) with at least one risk factor for clinically significant gastrointestinal...
Inflammatory bowel disease may be associated with increased risk of osteoporosis and osteopeia
1. In postmenopausal patients with ulcerative colitis (UC) or Crohn’s disease (CD), approximately one-third had osteoporosis while approximately 40% had...
Sotorasib plus panitumumab may be a promising treatment option for colorectal cancer
1. While not statistically significant, the use of sotorasib plus panitumumab may have a 30% relative risk reduction in the...