1. In this phase 3, randomized, placebo-controlled trial, an antiviral medication approved for treating smallpox (tecovirimat) did not accelerate clinical...
1. In this cohort study, the quadrivalent human papillomavirus (HPV) vaccine provides strong, long-lasting protection against invasive cervical cancer, with...
1. In this randomized controlled trial, neither metformin nor ursodeoxycholic acid improved recovery from long COVID compared with placebo in...
1. Poly-L-lysine (PLL)-coated catheters are well-tolerated, safe, and noninferior in preventing bacteriuria compared to noble metal alloys (NMA)-coated catheters in...
1. Among patients with sepsis-associated encephalopathy, propofol monotherapy was associated with lower one-year all-cause mortality compared to no sedation therapy....
1. Mobile telemedicine was associated with significantly higher chances of initiating hepatitis C virus (HCV) treatment and achieving viral clearance...
1. Adjunctive fluoxetine significantly reduced vasopressor duration and ICU length of stay in patients with severe sepsis. 2. Fluoxetine improved...
1. Children and adolescents with chronic medical conditions have a significantly higher risk of invasive pneumococcal disease, particularly those who...
1. Appendectomy was associated with a higher risk of non-typhoidal Salmonella infection in children. Evidence Rating Level: 2 (Good) Study...
1. Lyme disease (LD) is associated with substantial health care costs, with per-patient direct costs consistently high across several analytic...
Over the past 30 years, the transition from print to digital media has contributed to an exponential increase in medical literature. In response, 2 Minute Medicine presents 160+ authoritative, physician-written summaries of the most cited landmark trials in medicine.
