Nephrology

Reports of high-impact nephrology studies by medical professionals

[BMJ] Kidney stones associated with increased risk of end-stage renal disease

Image: CC/James Heilman. Stone in kidney (arrow), CT scan.  Primer: Kidney stones are a commonly encountered clinical problem, and while there is limited evidence linking...

[THE LANCET] Severe chronic kidney disease patients have higher coronary risk than diabetics. Time...

Image: CC/PD. Enlarged kidney (drawing).  Primer: Coronary heart disease (CHD) “equivalent”, a term used to describe some trait or factor that results in a 10-year risk...

Gastric bypass surgery for the severely obese associated with higher diabetes remission versus nonsurgical...

Image: CC/MilitaryHealth Key study points: 1.    Patients undergoing Roux-en-Y gastric bypass surgery for severe obesity had higher rates of diabetes remission and lower risk of cardiovascular...

A simple, cost-effective test for monitoring lupus nephritis

Image: CC. Lupus nephritis Key findings: The spot protein:creatinine ratio, a reproducible, cost-effective, and elegant test, correlates well with the labourious 24-hour urinary total protein excretion...

The ALTITUDE trial: Aliskiren increases the risk of adverse events and stroke without any...

Image: CC Key study points:  There was no difference in the incidence of primary outcomes (cardiovascular death, cardiac arrest with resuscitation, nonfatal MI, nonfatal stroke, etc.)...

Tolvaptan, a vasopressin receptor 2 antagonist, shows promise in polycystic kidney disease (TEMPO trial)

Image: PD/CDC. Cystic kidneys, gross pathology.  1. Tolvaptan can slow progression of autosomal dominant polycystic kidney disease both in terms of kidney volume and kidney function.  2....

Peginesatide is noninferior to epoetin for anemia in hemodialysis patients [EMERALD Trials]

1. Hemodialysis patients who received peginesatide had similar hemoglobin levels and similar rates of adverse events as patients who received traditional epoetin treatments. Published today...

Procalcitonin levels linked with acute pyelonephritis

Image: PD 1. Serum procalcitonin (PCT) levels were significantly associated with acute pyelonephritis and subsequent renal scarring in children with febrile urinary tract infections (UTIs).  2....

Post-operative acute kidney injury more common in obese elderly

Image: PD 1. Very obese patients older than 65 had a 1.68 odds ratio (p=0.01) for acute kidney injury (AKI) compared with nonobese patients after...

Low birth weight linked to chronic kidney disease: review of the evidence

Image: PD 1. Low birth weight is identified as a risk factor for later life hypertension and chronic kidney disease (CKD). 2. Maternal health/nutrition, genetics, and...

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