Psychotherapy identified as most effective treatment for grief
1. In this systematic review and meta-analysis, psychotherapy was the most effective intervention, improving grief disorder symptoms, general grief, and...
Psychiatry
Reports of high-impact psychiatry studies by medical professionals
Fluoxetine may improve hemodynamic status and organ dysfunction in patients with severe sepsis
1. Adjunctive fluoxetine significantly reduced vasopressor duration and ICU length of stay in patients with severe sepsis. 2. Fluoxetine improved...
Perioperative esketamine may improve postoperative pain and mood outcomes after cesarean section
1. Intravenous esketamine provides effective adjunctive analgesia after cesarean delivery while also reducing postoperative inflammation and mood-related complications. 2. Esketamine...
An electronic intervention may increase chances of benzodiazepine cessation
1. An electronic intervention promoting self-management of benzodiazepine cessation significantly increased the chances of benzodiazepine cessation compared to placebo. Evidence...
Duloxetine is effective in refractory chronic cough
1. Duloxetine is significantly more effective than placebo at reducing refractory chronic cough (RCC) frequency and sensitivity. Evidence Rating Level:...
Baseline cannabis use may not be associated with abstinence from vaping
1. Among young adults, baseline cannabis use was not associated with nicotine vaping abstinence. 2. 12 weeks of varenicline were...
Middle-aged and older Canadians at high risk of obstructive sleep apnea may have worse mental health outcomes
1. Middle-aged and older Canadian adults at high risk of obstructive sleep apnea (OSA) had worse mental health outcomes than...
Higher dose extended-release buprenorphine may reduce opioid use in patients with heavy fentanyl use
1. In this randomized double-blind controlled trial, both the 100-mg and 300-mg doses of buprenorphine were effective and well-tolerated, with...
Drug-related pressure ulcers may be characterised by medication-related characteristics such as polypharmacy and medication changes rather than baseline immobility
1. Approximately one in nine hospitalised patients with pressure ulcers met criteria for definite drug-related pressure ulcers (DRPU), characterised by...
Sertraline is associated with a lower risk of opioid overdose compared to other selective serotonin reuptake inhibitors in patients taking hydrocodone
1. Sertraline appears to be the safest selective serotonin reuptake inhibitor (SSRI) option for patients taking hydrocodone because it is...
