Association of a genetic risk score with body mass index across several birth cohorts

1. This observational study found that BMI is associated with a genetic risk score calculated from multiple loci. 2. This association is present in both...

Respiratory symptoms frequent in smokers despite normal spirometry: The SPIROMICS study

1. Symptomatic smokers with preserved spirometric measurements had a significantly higher rate of respiratory exacerbations than both asymptomatic smokers with preserved spirometric measures and...

BMI linked with lowest mortality has increased over past few decades

1. The body mass index (BMI) associated with the lowest level of all-cause mortality increased by 3.3 over the past 3 decades in a...

Outcomes remain poor in locally advanced pancreatic cancer

1. Compared to induction chemotherapy alone, maintenance chemoradiotherapy did not prolong overall survival or time to disease progression in patients with locally advanced pancreatic...

Olaparib linked to increased response in metastatic, castration-resistant prostate cancer

1. In this phase II trial, use of the poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitor olaparib showed a positive response in a subset of metastatic...

Apgar score not predictive of mortality or neurological outcome

1. The Apgar score evaluates initial infant condition after delivery and helps direct need for any resuscitative measures. This joint policy from the American...

Gender differences in academic achievement exist in medicine

  1. This study found that women were less likely than men to be full professors, have first and last author publications, and have funding...

Imetelstat associated with rapid hematological responses in essential thrombocythemia

1. Imetelstat induced hematologic responses in 100% of essential thrombocythemia (ET) patients and prolonged treatment was associated with more gradual increases after the discontinuation of...

Long-term use of NSAIDs and aspirin linked to lower risk of colorectal cancer

1. From a case-control study, using nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin continuously for over 5 years was associated with lower risk of...
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