• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Gastroenterology

Cold snare polypectomy with continuous anticoagulant use does not increase bleeding risk

byCaitlyn HuiandDeepti Shroff Karhade
July 16, 2019
in Gastroenterology, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. In this randomized controlled trial, cold snare polypectomy with continuous anticoagulation does not increase bleeding risk when compared to hot snare polypectomy with heparin bridging.

2. The cold snare polypectomy procedure had shorter procedure time per lesion and decreased length of hospital stays in comparison to hot snare polypectomy.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Polypectomy is a procedure utilized to reduce risk of morbidity and mortality associated with colorectal cancer in patients. The authors of this randomized controlled trial compared cold snare polypectomy (CSP) with hot snare polypectomy (HSP) and the risk of bleeding in patients on anticoagulant therapy. CSP does not involve electrocautery and has been found to result in reduced bleeding in patients receiving warfarin. In comparing outcomes between continuous administration of anticoagulants (CA) with CSP (CA + CSP) and periprocedural heparin bridging (HB) with HSP (HB + HSP) for subcentimeter colorectal polyps, no increased bleeding risk was found with CA + CSP. Mean hospitalization period and procedure length were found to be longer in the HB + HSP group.  One of the limitations of this randomized controlled trial was that patients and physicians were not blinded regarding treatment arms. Further, the results may not be fully generalizable to all patients undergoing polypectomy, as only patients with subcentimeter polyps were included in this study.

Click to read the study, published today in Annals of Internal Medicine

Relevant Reading: Colorectal polypectomy and endoscopic mucosal resection (EMR): European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline

In-Depth [randomized controlled trial]: In this study, the authors conducted an open-label, parallel, multicenter randomized controlled trial to determine the non inferiority of CA + CSP versus HB + HSP for treating subcentimeter colorectal polyps. The study was conducted in 30 Japanese academic or tertiary institutions between June 2016 to December 2017 and randomization occurred through a computer-generated system. The primary end point of the study was the incidence of polypectomy-related major bleeding. A total of 184 patients were enrolled in the study, with 90 in the HB + HSP arm and 92 in the CA + CSP arm. The authors observed an incidence of polypectomy-related major bleeding of 4.7% (95% CI, 0.2% to 9.2%) in the CA + CSP group and 12.0% (CI, 5.0% to 19.1%) in the HB + HSP group, Further, the intergroup difference was 7.2% (CI, -1.0% to 15.7%) and the risk ratio was 2.56 (CI, 0.84 to 7.84). Subgroup analysis showed noninferiority of polypectomy-related major bleeding in patients receiving warfarin and those taking DOACs. It was found that the mean procedure time per lesion was significantly shorter in the CA + CSP group compared to the HB + HSP arm of the study. The mean hospitalization period was also longer in the HB + HSP group.

RELATED REPORTS

Adenoma detection rate is inversely associated with post-colonoscopy colorectal cancer risk

Cold snare polypectomy associated with fewer complications than hot snare polypectomy

#VisualAbstract: Adagrasib provides antitumour activity against KRAS G12C mutant metastatic colorectal cancer both as monotherapy and in combination with cetuximab

Image: PD

©2019 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: andticoagulationbleeding riskcolonoscopycolorectal cancerpolypectomy
Previous Post

Quick Take: Disclosure of infant unsafe sleep practices by African American mothers in primary care settings

Next Post

Quick Take: 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm

RelatedReports

Benefits of high-intensity surveillance following colorectal adenoma removal likely outweigh costs
Chronic Disease

Adenoma detection rate is inversely associated with post-colonoscopy colorectal cancer risk

March 20, 2023
Racial differences in colorectal cancer survival linked to health at initial diagnosis
Chronic Disease

Cold snare polypectomy associated with fewer complications than hot snare polypectomy

February 27, 2023
#VisualAbstract: Telehealth treatment is effective in managing behavior problems in children with developmental delay
StudyGraphics

#VisualAbstract: Adagrasib provides antitumour activity against KRAS G12C mutant metastatic colorectal cancer both as monotherapy and in combination with cetuximab

January 27, 2023
Benefits of high-intensity surveillance following colorectal adenoma removal likely outweigh costs
Chronic Disease

Early-life body size not an independent risk factor for colorectal cancer

January 11, 2023
Next Post
Women with pregnancy-associated melanoma at greater risk of metastasis, recurrence

Quick Take: 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm

Microbe-rich environment associated with lower rates of asthma

Strong family relationships associated with improved asthma symptoms in dangerous neighborhoods

Flexible ICU family visits not effective at reducing delirium incidence

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Mycobacterium abscessus infections after cardiac surgery linked to hospital water system
  • The 2 Minute Medicine Podcast Episode 11
  • Wellness Check: Spirituality
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options