• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Dobutamine may reduce cerebral blood flow when administered

byRhianna DavisandAlex Chan
July 11, 2023
in Cardiology, Neurology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. In a cohort of young participants, dobutamine stress tests were found to reduce cerebral blood flow on magnetic resonance angiography.

Evidence Rating Level: 3 (Average)

Dobutamine is a sympathomimetic medication used in echocardiography and the acute care of congestive heart failure. Previous research has not established whether this medication impacts cerebral blood flow (CBF). This self-controlled study included 48 participants, aged 23 to 34 years, all non-smokers, with no previous cardiovascular or cerebrovascular disease. Magnetic resonance angiography (MRA) with 3D pseudo-continuous arterial spin labeling was used to assess CBF before and during a dobutamine stress test. MRA results were independently assessed by two radiologists. Compared to the resting state, CBF was significantly lower in both gray and white matter during the stress test, particularly in the anterior circulation (voxel level P<0.001, pixel level P<0.05). Factors associated with a greater reduction in cerebral blood flow during the test included high BMI (OR, 5.80; 95% CI, 1.60–21.01; P=0.008) and lower systolic blood pressure (SBP) (OR, 0.64; 95% CI, 0.45–0.92; P=0.014). This study determined that dobutamine-induced stress decreased CBF, particularly in the anterior brain of those with higher BMIs and low SBP. Given that the study only included young, healthy adults, the results cannot be generalized to a broader population. Further research is needed to determine whether dobutamine impacts CBF when used for patients who are older or those with chronic conditions, including congestive heart failure. 

Click to read the study in BMC Medicine

Image: PD

©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

RELATED REPORTS

#VisualAbstract: Routine Cerebral Embolic Protection Did Not Reduce Stroke Incidence during Transcatheter Aortic-Valve Implantation

The Scan by 2 Minute Medicine®: Celebrity diagnoses spur screenings, athlete mental-health push, reality-TV heart lesson, and a sitcom PSA wave

Early acetaminophen use reduces mortality risk in patients with sepsis-associated encephalopathy

Tags: cardiologydobuatmineneurology
Previous Post

A dual-chamber leadless pacemaker provided reliable long-term atrioventricular synchrony

Next Post

Several factors influenced the mental health of healthcare workers during the COVID-19 pandemic

RelatedReports

#VisualAbstract: Routine Cerebral Embolic Protection Did Not Reduce Stroke Incidence during Transcatheter Aortic-Valve Implantation
All Specialties

#VisualAbstract: Routine Cerebral Embolic Protection Did Not Reduce Stroke Incidence during Transcatheter Aortic-Valve Implantation

July 3, 2025
The Scan by 2 Minute Medicine®:  Ultra-Trail du Mont-Blanc, Taylor Swift, NBA rookie Chet Holmgren and Magic Mushrooms!
The Scan by 2 Minute Medicine®

The Scan by 2 Minute Medicine®: Celebrity diagnoses spur screenings, athlete mental-health push, reality-TV heart lesson, and a sitcom PSA wave

July 2, 2025
Emergency

Early acetaminophen use reduces mortality risk in patients with sepsis-associated encephalopathy

July 1, 2025
Quick Take: Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial
Weekly Rewinds

2 Minute Medicine Rewind June 30, 2025

June 30, 2025
Next Post

Several factors influenced the mental health of healthcare workers during the COVID-19 pandemic

#VisualAbstract: Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis

#VisualAbstract: Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis

Majority of pediatric medication-related visits to emergency department are preventable

Cyclophosphamide-tacrolimus-mycophenolate mofetil is an effective prophylaxis against graft-versus-host disease

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Artificial intelligence based clinical decision systems are safe and effective for diabetes management
  • Epic Launchpad propels generative-AI into everyday hospital routines
  • #VisualAbstract: Routine Cerebral Embolic Protection Did Not Reduce Stroke Incidence during Transcatheter Aortic-Valve Implantation
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.