• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Improved calculations suggest major changes to statin, aspirin, and blood pressure medication prescribing

byCaitlyn HuiandDeepti Shroff Karhade
June 6, 2018
in Cardiology, Chronic Disease, Endocrinology, Nephrology, Public Health
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.

2. Many Americans, especially those of African American descent, may require reduction and alteration to their statin, aspirin, and/or blood pressure medication.

Evidence Rating Level: 2 (Good)

Study Rundown: Cardiovascular disease (CVD) affects many people worldwide. Treatment for such disease is currently based on 10-year risk estimates, which were derived from five cohort studies conducted in 2013 that generated pooled cohort equations. However, recently these studies have become controversial due to reports on poor risk estimation. The authors of this study aimed to improve the clinical accuracy of CVD risk prediction by revising the 2013 PCEs with newer data and statistical methods. Generally, it was observed that this method of revised PCEs could improve the accuracy of CVD risk estimates. This study has several limitations. First, it is possible that the definition of high risk and low risk utilized in this study may still result in overestimations of patients in the high-risk category. Further, the definition of CVD outcome in this study did not incorporate heart failure or coronary revascularization. Finally, these results may necessitate further reproduction in other studies prior to revision of guidelines.

Click to read the study in Annals of Internal Medicine

Relevant Reading: Comparisons of the Framingham and Pooled Cohort Equation Risk Scores for Detecting Subclinical Vascular Disease in Blacks Versus Whites.

In-Depth [prospective cohort]: The authors of this study compared the original PCEs from 2013 with 2 new alternatives. The alternatives included a revision that used the same methods as in 2013 but applied to updated cohort data, as well as a revision that altered the derivation to address some of the statistical methodological concerns raised regarding the 2013 studies. The patient population included in the study reflected that of the patient population from the 2013 studies. It was observed that the previous calculations might have significantly overestimated risk of CVD in patients. For example, in African American adults, the overestimate of risk was especially significant. 33% of this population had extreme risk estimates (< 70% or > 250% those of Caucasian adults with the otherwise-identical risk factor values. On average, it was determined that the 2013 PCEs overestimated risk by 20% across all risk groups.

RELATED REPORTS

Mediterranean diet superior to low-fat diet in secondary prevention of cardiovascular events

Systematic review and meta-analysis of statin-induced reduction in LDL-C demonstrates modest absolute benefits

Low- and no-calorie sweetened beverages associated with reduced body weight compared to sugar-sweetened beverages: a systematic review and meta-analysis

Image: PD

©2018 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: cardiovascular risk
Previous Post

Survey-based priming intervention linked to improved communication and goals-of-care discussions amongst patient-clinician pairs

Next Post

Intensive management for sicker patients increases outpatient care but not costs

RelatedReports

FDA-approved weight loss medications associated with weight loss at one year
Cardiology

Mediterranean diet superior to low-fat diet in secondary prevention of cardiovascular events

May 25, 2022
Implementation of pneumococcal vaccine programs linked to decreased antibiotic prescription
Cardiology

Systematic review and meta-analysis of statin-induced reduction in LDL-C demonstrates modest absolute benefits

April 7, 2022
Added sugar intake associated with mortality from cardiovascular disease
Cardiology

Low- and no-calorie sweetened beverages associated with reduced body weight compared to sugar-sweetened beverages: a systematic review and meta-analysis

March 16, 2022
Cardiology

Higher sodium and lower potassium urinary excretion increase cardiovascular risk

February 1, 2022
Next Post

Intensive management for sicker patients increases outpatient care but not costs

Recurrent hemoptysis is effectively treated by bronchial artery embolization

Recombinant human pentraxin 2 slows the decline in lung function for patients with idiopathic pulmonary fibrosis

Isolated mild/moderate thrombocytopenia may not require intervention

Isolated mild/moderate thrombocytopenia may not require intervention

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Cognitive behavioral therapy efficacious for treatment of comorbid posttraumatic headache and posttraumatic stress disorder symptoms among US veterans
  • Sickle cell trait associated with preexisting kidney comorbidities and increased COVID-19 mortality
  • Adding atezolizumab to standard of care treatment for human epidermal growth factor receptor 2 (HER2) positive early breast cancer does not improve pathologic response outcomes
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.