• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Emergency

Primary trabeculectomy associated with similar outcomes as medical management for advanced glaucoma

byBrian DoughertyandAlex Chan
May 18, 2021
in Emergency, Ophthalmology, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. At 24 months, visual quality of life for patients with advanced open angle glaucoma was similar if treated initially with trabeculectomy or with medical management.

Evidence Level Rating: 1 (Excellent)

Glaucoma is one of the leading causes of blindness in the U.S., and the incidence is increasing due to an aging population. Open angle glaucoma in particular is difficult to manage, with some practitioners opting for trabeculectomy as a primary intervention, though there are a paucity of robust data to support this, especially among patients presenting with advanced disease. This multicenter, randomized controlled trial compared primary medical management with primary trabeculectomy for patients presenting with untreated open angle glaucoma. The primary outcome was quality of life as measured by the Visual Function Questionnaire-25 (VFQ-25) at 24 months. 227 patients were randomized to undergo trabeculectomy (mean [SD] age = 67 [12.2] years, 69% male) and 226 to receive medical management (mean [SD] age = 68 [12.4] years, 65% male). It was found that, at 24 months, there was no significant difference in mean VFQ-25 scores between the trabeculectomy and medical management cohorts (85.4±13.8 vs. 84.5±16.3, mean difference 1.06, 95% CI -1.32 to 3.34, p = 0.38). The mean intraocular pressure, however, was significantly lower in the trabeculectomy cohort. Adverse events were similar between the two cohorts. In all, no difference between trabeculectomy and medical management for the treatment of advanced open angle glaucoma was seen. Surgery was safe and effective at reducing intraocular pressure. Such findings will help guide decision making for patients presenting with advanced disease.

Click to read the study in BMJ

Image: PD

©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

RELATED REPORTS

Medbridge turns any phone into a motion-capture coach for at-home rehab

Cerebral embolic protection does not decrease stroke incidence in TAVI patients

Minimally invasive surgery is beneficial for epithelial ovarian cancer 

Tags: glaucomaOphthalmologySurgery
Previous Post

#VisualAbstract: Rifapentine-moxifloxacin noninferior to standard of care treatment for pulmonary tuberculosis

Next Post

Higher prevalence of gender-diverse youth than previously reported

RelatedReports

Active sexting among teens related to sexual activity
AI Roundup

Medbridge turns any phone into a motion-capture coach for at-home rehab

July 10, 2025
Cerebral protection device effective in patients undergoing transcatheter aortic valve implantation
Cardiology

Cerebral embolic protection does not decrease stroke incidence in TAVI patients

July 8, 2025
All Specialties

Minimally invasive surgery is beneficial for epithelial ovarian cancer 

July 4, 2025
Quick Take: Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial
Weekly Rewinds

2 Minute Medicine Rewind June 30, 2025

June 30, 2025
Next Post
Mental health parity law associated with financial protection for children

Higher prevalence of gender-diverse youth than previously reported

“No Evidence of Disease Activity” may be useful goal in multiple sclerosis

Early intervention for cerebral palsy should begin at diagnosis or in children meeting high risk criteria – International Clinical Practice Guideline

Compliance-linked incentives increase infant immunizations rates in rural India

BNT162b2 mRNA vaccine shows benefit against symptomatic and asymptomatic SARS-CoV-2 infection 

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Vaporized nicotine products may be effective for smoking cessation among people with social disadvantage
  • #VisualAbstract: Brain Activation Measured on Functional MRI Predicts Response to Certolizumab, a TNF Inhibitor, in Rheumatoid Arthritis
  • 2 Minute Medicine Rewind July 14, 2025
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.