Tag: Surgery

1. Following emergency general surgery procedures, frail patients had poorer clinical outcomes such as higher mortality, non-home discharge rates, and hospital readmissions, as well as greater hospital costs. Evidence Rating Level: 2 (Good) Emergency general surgeries (EGS) carry greater risk of mortality and other poorer clinical outcomes, due to the involvement...

Real time remote symptom monitoring during chemotherapy for cancer: European multicentre randomised controlled trial (eSMART) 1. A daily remote symptom monitoring system reduced both the physical and psychological burden of chemotherapy side effects across six chemotherapy cycles, compared to standard care. Evidence Rating Level: 1 (Excellent) Individuals undergoing chemotherapy can experience numerous...

1. This phase III drug trial showed that dexamethasone does not significantly reduce risk of adverse events and death following major non-cardiac surgery. 2. Secondary safety outcomes were comparable between the dexamethasone and placebo groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Major surgery has potential major complications, such as shock, infection,...

1. Using a restrictive fluid resuscitation strategy for early to mild post-partum hemorrhage yielded similar hemodynamic outcomes as a liberal fluid resuscitation strategy. Evidence Rating Level: 1 (Excellent) Postpartum hemorrhage (PPH) is a leading cause of maternal death internationally. Currently, the PPH guidelines set by the Royal College of Obstetricians and...

Burden of ischemic stroke in patients with congenital heart disease: A nationwide, case‐control study 1. A nationwide Swedish study demonstrated that patients with congenital heart disease are at an increased risk of developing ischemic stroke compared to controls. Evidence Rating Level: 3 (Average) Congenital heart disease (CHD) is the most common...

1. Most injured children and adolescents return to baseline functional status by discharge. 2. Pediatric populations with extremity injuries or severe head injuries were at greatest risk of functional impairment at discharge. Evidence Rating Level: 2 (Good) Pediatric injuries often result in short- and long-term functional impairments, negatively impacting quality of life...

Risk factors for acute kidney injury and mortality in high risk patients undergoing cardiac surgery 1. In a retrospective cohort study, several pre-operative and operative factors were found to be associated with acute kidney injury and future mortality. Evidence Rating Level: 2 (Good) Acute kidney injury (AKI) is a significant cause...

1. At 24 months, visual quality of life for patients with advanced open angle glaucoma was similar if treated initially with trabeculectomy or with medical management. Evidence Level Rating: 1 (Excellent) Glaucoma is one of the leading causes of blindness in the U.S., and the incidence is increasing due to an...

1. Inflammatory bowel disease (IBD) is associated with increased risk of coronary microvascular dysfunction (CMD). 2. Surgical intestinal resection in IBD patients improved coronary flow velocity reserve (CFVR), a measure of CMD. Evidence Rating Level: 2 (Good) Inflammatory bowel diseases (IBDs) include conditions such as Crohn Disease (CD) and Ulcerative Colitis (UC)....

Association of oral corticosteroid bursts with severe adverse events in children 1. Among a large cohort of children in Taiwan, oral corticosteroids prescribed for <14 days were associated with an increased risk of gastrointestinal (GI) bleeds, sepsis, and pneumonia during the first month of therapy initiation. Evidence level rating: 2...