Tag: Ophthalmology

1. At 24 months, visual quality of life for patients with advanced open angle glaucoma was similar if treated initially with trabeculectomy or with medical management. Evidence Level Rating: 1 (Excellent) Glaucoma is one of the leading causes of blindness in the U.S., and the incidence is increasing due to an...
Cardiovascular safety of hydroxychloroquine in veterans with rheumatoid arthritis 1. Among a large, matched cohort of veterans with rheumatoid arthritis, initiation of hydroxychloroquine was not associated with a higher risk of adverse cardiovascular events or death. Evidence Rating Level: 1 (Excellent) In anecdotal case reports, hydroxychloroquine (HCQ) has been reported to prolong...
1. In comatose patients in the ICU, polyethylene eye covers were superior to artificial teardrops and normal saline eye drops for the reduction in incidence and severity of ocular surface diseases. Evidence Rating Level: 1 (Excellent) For patients who are critically ill or comatose, eye care is often not considered a...
1. Hypertension and overweight to obese BMI in children were associated with changes in retinal microvasculature. Evidence Rating Level: 2 (Good) Hypertension and obesity, two of the most important risk for cardiovascular diseases, are growing increasingly prevalent in childhood due to a shift in health behaviours towards a sedentary lifestyle, poor...
1. Following a period of house confinement and online school due to COVID-19, the prevalence of myopia increased between 1.3 and 3.8 times in 6-8 year old children, and the mean spherical equivalent refraction (SER) decreased by -0.3 diopters compared to previous years. 2. Children aged 9-13 years did not...
1. For non-experts, sensitivity in diagnosing CMV retinitis ranged from 64.0% to 95.5% and specificity ranged from 65.6% to 92.5%. 2. When compared to the expert consensus as a standard, mean sensitivity and specificity for non-experts were 93.2% and 88.4% respectively. Evidence Rating Level: 2 (Good) Study Rundown: Cytomegalovirus (CMV) retinitis is a serious complication...
1. Both the 0.35mg and 0.7mg dexamethasone dosing led to a significant increase in visual acuity compared to sham. 2. Central retinal thickness, a measure of the extent macular edema, was decreased significantly in the 0.35mg and 0.7mg dexamethasone treatment groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Diabetic macular edema (DME),...
Image: PD 1. A significant association was observed with patients who were exposed to the outdoors for over 11 hours during the high school to 24 year period. 2. Although not statistically significant, females living closer to the equator who spent significant amount of time outdoors were found to have...
Image: PD 1. 8 predictors (age, sex, education level, race, smoking status, presence of pigment abnormality, soft drusen, and maximum drusen size) were utilized to create a macular risk scoring system (MRSS). 2. Area under the receiver operating characteristic (ROC) curve was excellent (internally validated c-index = 0.88; externally validated c-index...
Image: PD 1. At 24 months, frequency doubling perimetry (FDP) foveal sensitivity was significantly decreased in the placebo group (-1.9 dB) and increased in the group treated with Doxycycline (+1.8 dB, p=0.02). This difference was consistently observed beginning at 6 months. 2. There were no other significant differences between the placebo...