• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Infectious Disease

RSV vaccination in third trimester associated with significantly reduced infection risk in early months of life

byDavy LauandAlex Chan
November 17, 2020
in Infectious Disease, Obstetrics, Pediatrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. With 70% vaccination coverage, a 3rd trimester maternal vaccine for respiratory syncytial virus (RSV) was modelled to reduce RSV infection rates by 16.6% in infants younger than 3 months. 

2. Incidence rate of RSV infections in the first 6 months of life for infants born to unvaccinated mothers was 1.26 times that of those born to vaccinated mothers.

Evidence Rating Level: 2 (Good)

The respiratory syncytial virus (RSV) infects almost all children by their second birthday, and was responsible for 3.2 million hospitalisations in the year 2015 alone globally, for children younger than 5. Although there is currently no approved RSV vaccine, maternal immunisation in the third trimester of pregnancy ubiquitously used as a preventative strategy. However, RSV vaccines are expected to be short-lasting, making it important to study their public health implications through modelling frameworks. From past research, households have been identified as a significant contributor to RSV transmission, but modelling studies have not been conducted on high-income settings yet. The current study’s goal was to model the household-level impact of maternal RSV vaccines in a high-income country. This involved combining Australian census data with a model for RSV transmission, accounting for household and community population mixing, and defining the parameters for an infant’s immunity duration, which was found to depend on vaccination timing and the mother’s immunity duration. Overall, the results found that the largest benefit from maternal vaccination was for infants younger than 3 months, with a 16.6% reduction in infection incidence (interquartile range -14.2 to -19.8%), for a scenario of 70% vaccination coverage. For infants aged 3-6 months, the reduction was 5.3% (IQR -7.3 to 1%). All other age groups had similar incidence rates compared to no vaccination scenarios, with the exception of children aged 1-2, which had a predicted 2.8% increase in infection (IQR 0.3-5.8%). In conclusion, this study showed that maternal RSV vaccination can have a significant effect on lowering infection rates in infants younger than 3, but may have little impact in older age groups.

Click to read the study in BMC Medicine

Image: PD

RELATED REPORTS

Evaluating scar outcomes in pediatric burn patients following skin grafting 

Trimethoprim-sulfamethoxazole during pregnancy does not reduce risk of prematurity

Second-line TAF-based ART improves viral suppression in pediatric HIV

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: infectious diseaseobstetricspediatricsvaccination
Previous Post

Higher SARS-CoV-2 antibody titers in patients hospitalized with MIS-C

Next Post

#VisualAbstract: Efficacy and safety of short-term therapy with indigo naturalis for ulcerative colitis

RelatedReports

Pediatrics

Evaluating scar outcomes in pediatric burn patients following skin grafting 

June 26, 2025
Implementation of pneumococcal vaccine programs linked to decreased antibiotic prescription
Infectious Disease

Trimethoprim-sulfamethoxazole during pregnancy does not reduce risk of prematurity

June 9, 2025
Government-funded initiatives provide important supports to low-income HIV patients
Infectious Disease

Second-line TAF-based ART improves viral suppression in pediatric HIV

June 4, 2025
Being overweight and obese associated with increased incidence of chronic kidney disease
Chronic Disease

Worsening kidney function observed following SARS-CoV-2 infection in children

May 23, 2025
Next Post
#VisualAbstract: Adjuvant radiotherapy may worsen outcomes compared to salvage radiotherapy post radical prostatectomy

#VisualAbstract: Efficacy and safety of short-term therapy with indigo naturalis for ulcerative colitis

1 in 5 US women report delayed contraceptive initiation after sexual debut

Injectable contraceptives associated with the longest delays in return of normal fertility

#VisualAbstract: Adjuvant radiotherapy may worsen outcomes compared to salvage radiotherapy post radical prostatectomy

#VisualAbstract: Adjuvant radiotherapy may worsen outcomes compared to salvage radiotherapy post radical prostatectomy

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Seventh cervical nerve neurotomy may augment speech therapy in patients with chronic aphasia post-stroke
  • Time-restricted eating does not confer changes in sleep, mood, or quality of life
  • Commonly cited medication triggers may not increase risk of microscopic colitis among older adults
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.