• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Sigmoidoscopy reduces colon cancer risk for men, but not women

byCaitlyn HuiandDeepti Shroff Karhade
April 24, 2018
in Chronic Disease, Gastroenterology, Imaging and Intervention, Oncology, Public Health, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Sigmoidoscopy was associated with a reduction in the prevalence of colon cancer mortality in men.

2. Sigmoidoscopy did not appear to have a significant protective effect for women with respect to decreasing the rates of colorectal cancer.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Colorectal cancer (CRC) is one of the most common cancers in men and women in the United States. Current practice guidelines recommend CRC screening in adults aged 50 to 70, through colonoscopy, flexible sigmoidoscopy, or a fecal occult blood test. Although sigmoidoscopy is one of the current screening methods, its efficacy remains unclear in men and women, as further studies with longer-term follow-up are needed. Therefore, the purpose of this study was to evaluate the effectiveness of flexible sigmoidoscopy in terms of screening for CRC in men and women. Overall, the results of the study suggested that while sigmoidoscopy reduces colon cancer risk for men, this trend is not apparent in women. One of the study’s strengths is the long-term follow-up, where participants were evaluated at approximately 15 years. Limitations of the study include the fact that data on socioeconomic status and ethnicity were not available. While the study was randomized, these factors may still have had an influence on the results. Furthermore, results of this study may not be generalizable to all populations.

Click to read the study, published in Annals of Internal Medicine

Relevant Reading: Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: pooled analysis of randomised trials

RELATED REPORTS

#VisualAbstract: Encorafenib, Cetuximab, and mFOLFOX6 Improves Survival in BRAF-Mutated Colorectal Cancer

2MM: AI Roundup- AI Cancer Test, Smarter Hospitals, Faster Drug Discovery, and Mental Health Tech [May 2nd, 2025]

Sotorasib plus panitumumab may be a promising treatment option for colorectal cancer

In-Depth [randomized controlled trial]: The authors of this study conducted a randomized controlled trial to evaluate the efficacy of flexible sigmoidoscopy in terms of CRC screening. The trial involved men and women aged 50 to 64 without CRC at baseline, with primary outcomes including CRC incidence and mortality stratified by sex. In general, sigmoidoscopy was associated with a reduced rate of mortality from CRC in men. For example, the absolute risk for death of CRC in men was 0.49% for the screening group, compared to 0.81% for the control group (risk difference, -0.33 percentage point [CI, -0.49 to -0.16 percentage point]; HR, 0.63 [CI, 0.47 to 0.83]). This trend was not apparent for the women involved in the study. Specifically, the treatment group for women had an absolute risk of death of 0.60%, while the control group had an absolute risk of death of 0.59%. The screening adherence rates of the study were 64.7% in women and 61.4% in men.

Image: CC/Wiki

©2018 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: cancer screeningcolonoscopycolorectal cancerSigmoidoscopy
Previous Post

Rustbelt states may have greatest racial disparities between black and white men for firearm homicides

Next Post

2 Minute Medicine Rewind April 23, 2018

RelatedReports

#VisualAbstract: Encorafenib, Cetuximab, and mFOLFOX6 Improves Survival in BRAF-Mutated Colorectal Cancer
StudyGraphics

#VisualAbstract: Encorafenib, Cetuximab, and mFOLFOX6 Improves Survival in BRAF-Mutated Colorectal Cancer

June 13, 2025
2MM: AI Roundup- AI Cancer Test, Smarter Hospitals, Faster Drug Discovery, and Mental Health Tech [May 2nd, 2025]
AI Roundup

2MM: AI Roundup- AI Cancer Test, Smarter Hospitals, Faster Drug Discovery, and Mental Health Tech [May 2nd, 2025]

May 21, 2025
Benefits of high-intensity surveillance following colorectal adenoma removal likely outweigh costs
Gastroenterology

Sotorasib plus panitumumab may be a promising treatment option for colorectal cancer

April 16, 2025
#VisualAbstract: Invitation to Fecal Immunochemical Test is Noninferior to Colonoscopy Screening in Colorectal Cancer Mortality
StudyGraphics

#VisualAbstract: Invitation to Fecal Immunochemical Test is Noninferior to Colonoscopy Screening in Colorectal Cancer Mortality

April 7, 2025
Next Post
Development of a risk index for colorectal cancer screening

2 Minute Medicine Rewind April 23, 2018

Elevated FGF-23 associated with recurrent cardiovascular events after acute coronary syndrome

Computed tomography improves diagnostic certainty in the emergency department

Understanding in-hospital mortality after stroke in pediatric patients

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Intravaginal conjugated oestrogen does not improve continuation rate of ring pessary use
  • Artificial intelligence based clinical decision systems are safe and effective for diabetes management
  • Epic Launchpad propels generative-AI into everyday hospital routines
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.