Tag: cancer screening

1. Magnetic resonance imaging with targeted and standard biopsy was non-inferior for the detection of clinically significant cancers compared to standard biopsy only. 2. The detection of clinically insignificant cancers was less in the MRI group. Evidence Rating Level: 1 (Excellent) Study Rundown: Prostate cancer screening reduces prostate cancer mortality but has high...

1. Magnetic resonance imaging with targeted and standard biopsy was non-inferior for the detection of clinically significant cancers compared to standard biopsy only. 2. The detection of clinically insignificant cancers was less in the MRI group. Evidence Rating Level: 1 (Excellent) Study Rundown: Prostate cancer screening reduces prostate cancer mortality but has...

1. Both CA125 serum and transvaginal ultrasound annual screening did not significantly reduce deaths due to ovarian or tubal cancer compared to no annual screening. 2. The incidence of stage III-IV disease was decreased in the CA125 screening group compared to no annual screening. Evidence Rating Level: 1 (Excellent) Study Rundown: Ovarian cancer has a...

1. Both CA125 serum and transvaginal ultrasound annual screening did not significantly reduce deaths due to ovarian or tubal cancer compared to no annual screening. 2. The incidence of stage III-IV disease was decreased in the CA125 screening group compared to no annual screening. Evidence Rating Level: 1 (Excellent) Study Rundown:...

1. Gastrointestinal, genitourinary, or bronchopulmonary bleeding in anticoagulated patients with atrial fibrillation have been associated with higher rates of respective cancer diagnoses. Evidence Rating Level: 2 (Good) Recent registry data suggests that diagnoses of atrial fibrillation (AF) have been associated with higher incidence rates of cancer. Bleeding episodes in anticoagulated patients...

Insufficient maternal iodine intake associated with subfecundity, reduced foetal growth, and adverse pregnancy outcomes in the Norwegian Mother, Father and Child Cohort Study 1. Low iodine intake associated with decreased subfecundity, reduced fetal growth, increased preterm delivery, and increased preeclampsia. Evidence Rating Level: 2 (Good) The thyroid gland is important in fertility...

1. In this observational study involving women aged 70 to 84 years with a life expectancy of at least 10 years, continuing screening past the age of 75 offered no survival benefits versus stopping screening. 2. Participants in the “stop screening” group were, on average, more likely to be diagnosed...

1. In this study comparing three prominent lung cancer screening strategies, all were found to be cost-effective, yielding incremental cost-effectiveness ratios of under $100,000/quality adjusted life-year gained, the commonly referenced U.S. willingness-to-pay threshold. 2. As the maximum age for screening eligibility increased, greater reductions in cancer mortality were realized but...

1. Prediction tool may help physicians better personalize screening discussions with patients. 2. Benefits of the prediction tool, low-dose computer tomography (LDCT), was shown to be highest in patients with higher-risk for lung cancer and longer life expectancy. Evidence Rating Level: 2 (Good) Study Rundown: Lung cancer is one of the most...

1. Sigmoidoscopy was associated with a reduction in the prevalence of colon cancer mortality in men. 2. Sigmoidoscopy did not appear to have a significant protective effect for women with respect to decreasing the rates of colorectal cancer. Evidence Rating Level: 1 (Excellent) Study Rundown: Colorectal cancer (CRC) is one of the...