acute myeloid leukemia (AML) | 2 Minute Medicine

Imatinib safe and effective as long-term treatment for chronic myeloid leukemia: The IRIS trial

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Delaying intrathecal therapy in leukemia may preclude need for cranial radiotherapy

Ivosidenib and azacitidine provide significant benefits in IDH1-mutated acute myeloid leukemia

byDavid Xiangand1 others

May 13, 2022

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1. Compared to placebo and azacytidine, the combination of ivosidenib and azacitidine demonstrated significant clinical benefit for IDH1-mutated acute myeloid ...

Prophylactic platelet transfusions prevent bleeding in hematologic cancers

Ivosidenib and azacitidine showed significant clinical benefit in newly diagnosed IDH1-mutated acute myeloid leukemia

byJohan Pushaniand1 others

May 2, 2022

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1. Event-free survival and median overall survival were significantly longer in the combination group 2. Febrile neutropenia and infections occurred ...

#VisualAbstract Intensive chemotherapy is associated with better long-term survival in older patients with acute myeloid leukemia

byKathleen Lau

November 27, 2021

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$#VisualAbstract Adding uproleselan to chemotherapy in patients with relapsed or refractory acute myeloid leukemia was well-tolerated with high remission rates$

#VisualAbstract Adding uproleselan to chemotherapy in patients with relapsed or refractory acute myeloid leukemia was well-tolerated with high remission rates

byKathleen Lau

September 30, 2021

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#VisualAbstract Ivosidenib or enasidenib combined with intensive chemotherapy were well-tolerated and showed encouraging clinical activity in newly diagnosed mIDH1/mIDH2 acute myeloid leukemia

byKathleen Lau

April 25, 2021

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Fluorophores enhance visualization for image-guided surgery [PreClinical]

Whole-genome sequencing more accurate than cytogenetic analysis in myeloid cancers

bySze Wah Samuel Chanand1 others

March 10, 2021

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1. Whole-genome sequencing for myeloid cancers, compared to standard cytogenic analysis, was able to more effectively risk-stratify cytogenic cases. 2. ...

Quick Take: Factors associated with successful discontinuation of immune suppression after allogenic hematopoietic cell transplantation

Oral azacytidine maintenance therapy improved survival outcomes in patients with acute myeloid leukemia

byRicha Sharmaand1 others

January 24, 2021

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1. Oral azacytidine also known as CC-486 has been found to improve survival outcomes in patients with acute myeloid leukemia. ...

#VisualAbstract Oral poly(ADP-ribose) polymerase inhibitors were associated with an increased risk of myelodysplastic syndrome and acute myeloid leukaemia over placebo treatment in patients with cancer

byKathleen Lau

January 22, 2021

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Mutation linked with decrease in cutaneous diffuse large B-cell lymphoma

Patients with hematological malignancies and concomitant COVID-19 have worse health outcomes

byNeel Mistryand1 others

December 23, 2020

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1. Older age, progressive disease status, diagnosis of acute myeloid leukemia, non-Hodgkin lymphoma, or plasma cell neoplasms, and severe or ...

Tag: acute myeloid leukemia (AML)

2 Minute Medicine Rewind September 1, 2025

Ivosidenib and azacitidine provide significant benefits in IDH1-mutated acute myeloid leukemia

Ivosidenib and azacitidine showed significant clinical benefit in newly diagnosed IDH1-mutated acute myeloid leukemia

#VisualAbstract Intensive chemotherapy is associated with better long-term survival in older patients with acute myeloid leukemia

#VisualAbstract Adding uproleselan to chemotherapy in patients with relapsed or refractory acute myeloid leukemia was well-tolerated with high remission rates

#VisualAbstract Ivosidenib or enasidenib combined with intensive chemotherapy were well-tolerated and showed encouraging clinical activity in newly diagnosed mIDH1/mIDH2 acute myeloid leukemia

Whole-genome sequencing more accurate than cytogenetic analysis in myeloid cancers

Oral azacytidine maintenance therapy improved survival outcomes in patients with acute myeloid leukemia

#VisualAbstract Oral poly(ADP-ribose) polymerase inhibitors were associated with an increased risk of myelodysplastic syndrome and acute myeloid leukaemia over placebo treatment in patients with cancer

Patients with hematological malignancies and concomitant COVID-19 have worse health outcomes

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