Solanezumab does not slow cognitive decline in patients with Alzheimer’s disease
1. In this randomized controlled trial, over a period of 240 weeks, solanezumab did not slow cognitive decline as compared ...
Tag: amyloid
Patisiran is effective in treatment of hereditary transthyretin amyloidosis.
1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18 ...
Amyloid-beta (1-40) is a strong predictor of mortality in acute coronary syndrome
1. Patients with the highest Aβ40 also had the worst non-ST-segment elevation acute coronary syndrome (NSTE-ACS) risk profile. 2. Greater ...
Midlife vascular risk factors linked with higher brain amyloid in later life
1. In this prospective cohort study, the presence of vascular risk factors during midlife were associated with higher brain amyloid ...
2 Minute Medicine Rewind June 27, 2016
Association between achieved low-density lipoprotein levels and major adverse cardiac events in patients with stable ischemic heart disease taking ...
Amyloid pathology may be detected decades prior to Alzheimer’s diagnosis
1. In this study, the presence of amyloid in patients without dementia was associated with age, APOE genotype, and presence ...
Amyloid may cause distant cerebral hypometabolism in Alzheimer’s
1. In a longitudinal study of 15 patients with Alzheimer’s disease (AD), regions of isolated cerebral hypometabolism detected by FDG-PET ...
Arterial stiffening associated with β-Amyloid deposition
Image: PD 1. Increased measures of systemic arterial stiffness were found to be significantly associated with a greater extent of ...
PET scans accurately identify amyloid deposition after traumatic brain injury
Image: PD 1. Amyloid plaques, similar to those found in Alzheimer’s disease were found in traumatic brain injury (TBI) victims. ...