Albuminuria shows a stronger association with kidney failure than proteinuria
1. In this individual-level meta-analysis, urinary albumin-creatinine ratio (UACR) had a stronger association with increased risk of kidney failure when ...
Tag: chronic disease
Multidomain rehabilitation after myocardial infarction improves outcomes in older adults
1. In this randomized controlled trial, a multidomain rehabilitation program significantly reduced cardiovascular death and unplanned cardiac hospitalizations in older ...
Aficamten is superior to metoprolol in the management of obstructive hypertrophic cardiomyopathy
1. In this randomized trial, aficamten monotherapy led to greater improvements in exercise capacity compared to metoprolol in patients with ...
Limiting antihypertensive use does not reduce mortality in nursing home residents with frailty
1. In this randomized clinical trial, among older nursing home residents with frailty who were being treated for hypertension with ...
Digitoxin improves outcomes in heart failure with reduced ejection fraction
1. Among patients with symptomatic chronic heart failure already on guideline-directed medical therapy (GDMT), digitoxin lowered all-cause mortality and hospital ...
An absence of cardiovascular risk factors is linked to over ten additional healthy years
1. In this large global cohort study, individuals aged 50 without five major cardiovascular risk factors (hypertension, hyperlipidemia, abnormal body ...
Significant body weight reduction with cagrilintide-semaglutide therapy
1. In this randomized controlled trial, the combination cagrilintide-semaglutide (CagriSema) resulted in significantly greater body weight reduction compared to either ...
Presymptomatic treatment of spinal muscular atrophy with risdiplam leads to improved functional outcomes
1. In this single-group trial, among infants predicted to develop type 1 spinal muscular atrophy (SMA) who were treated presymptomatically ...
Similar outcomes between lactated Ringer’s and normal saline for hospitalized patients
1. Among randomized hospitalized patients in this trial, routine use of lactated Ringer’s (LR) solution did not reduce the risk ...
Finerenone with empagliflozin beneficial for managing CKD and type 2 diabetes
1. Among patients with both chronic kidney disease (CKD) and type 2 diabetes (T2D) already on a renin-angiotensin system (RAS) ...
