Tag: coronary bypass

1. Patients undergoing coronary artery bypass grafting (CABG) who received a radial-artery graft rather than a saphenous-vein graft (both groups also received an internal-thoracic-artery graft) experienced fewer major adverse cardiac events at a mean follow-up of 60 months. 2. At a mean follow-up of 50 months, angiography showed patients in...
1. In this randomized controlled trial, saphenous vein graft patency after elective CABG was significantly improved in patients treated with ticagrelor plus aspirin versus aspirin alone after one year. 2. There was no significant difference in improvement in graft patency between ticagrelor and aspirin monotherapies. Evidence Rating: 1 (Excellent) Study Rundown: The...
1. Compared with placebo, levosimendan did not reduce the need for prolonged catecholamine infusion, use of left ventricular assist device, or renal replacement therapy in patients with low ejection fraction undergoing coronary artery bypass grafting with cardiopulmonary bypass Evidence Rating Level: 1 (Excellent) Study Rundown: Mortality after coronary artery bypass grafting...
1. In patients with diabetes and multivessel disease, coronary artery bypass grafting (CABG) was shown to be superior to percutaneous coronary intervention (PCI) with drug-eluting stents in reducing the risk of all-cause mortality and nonfatal myocardial infarction. 2. Patients treated with PCI experienced a smaller risk of nonfatal stroke, but...
1. Administration of fibrinogen concentrate in patients undergoing high-risk cardiac surgery did not significantly reduce intraoperative blood loss. Evidence Rating Level: 1 (Excellent) Study Rundown: Intraoperative bleeding remains one of the most common complications in cardiac surgery. Plasma fibrinogen deficiency often develops when the ongoing blood loss is substituted with red...
1. At 5-years of follow-up, there were no significant differences in the rates of mortality and cardiovascular outcomes when comparing patients treated with bilateral or single internal-thoracic-artery coronary-artery bypass grafting (CABG). 2. There was a significantly higher rate of sternal wound complications observed in the bilateral group compared to the single...
Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial Coronary artery bypass grafting (CABG) is the standard treatment for revascularization in patients with left main coronary artery disease. However, percutaneous coronary intervention (PCI) is being increasingly performed...
1. From a cohort study of Danish patients presenting with acute coronary syndrome, early invasive revascularization interventions were associated with reduced cardiac mortality when compared to conservative invasive strategies. 2. Early intervention was also associated with decreased all-cause mortality and re-hospitalization within 60 days compared to conservative intervention. Evidence Rating Level:...
1. Compared to patients treated with “on-pump” coronary artery bypass grafting, patients treated with “off-pump” surgery demonstrated a decreased rate of acute kidney injury. 2. However, no difference in loss of kidney function was noted between “on-pump” and “off-pump” techniques at 1-year post surgery.  Evidence Rating Level: 1 (Excellent)  Study Rundown: Coronary...
Image: PD  1. High circulating IGF-1 and several cardiac stem cell (CSC) markers correlate with positive ventricular remodeling after revascularization.  2. High pre-op HGF and VEGF may protect damaged myocardium prior to revascularization.  Evidence Rating Level: 2 (Good)  Study Rundown: Long-term clinical outcomes of patients undergoing coronary artery bypass surgery are difficult to...