Tag: Coronavirus

1. The proportion of patients with one or more symptom sequelae significantly decreased from 6 months (68%) to 12 months (49%). 2. 88% of patients had returned to employment within 12 months of hospital discharge. Evidence Rating Level: 2 (Good) Study Rundown: Although COVID-19-related hospitalization is common, little is known about the long-term complications among...
1. The proportion of patients with one or more symptom sequelae significantly decreased from 6 months (68%) to 12 months (49%). 2. 88% of patients had returned to employment within 12 months of hospital discharge. Evidence Rating Level: 2 (Good) Study Rundown: Although COVID-19-related hospitalization is common, little is known about the...
1. Risk of acute myocardial infarction and ischemic stroke was increased during the first two weeks following a COVID-19 infection compared to the general population. 2. The risk of developing acute myocardial infarction and ischemic stroke decreased in weeks 3-4 following a COVID-19 infection compared to the first two weeks. Evidence...
1. Approximately 8.5 million children were estimated to have missed DTP3 and MCV1 vaccinations in 2020 due to the global pandemic. 2. The largest disruptions were seen in April and May 2020, with some countries recovering to annual targets by the end of 2020. Evidence Rating Level: 3 (Average) Study Rundown: The...
1. Older age, male sex, and pre-existing comorbidities were independent risk factors for developing complications following COVID-19 infection. 2. The most common complications included renal, complex respiratory, systemic, and cardiovascular. Evidence Rating Level: 2 (Good)  Study Rundown: Patients hospitalized with COVID-19 are likely to develop in-hospital complications which may worsen their prognosis....
1. Retrospective analysis of hospital records showed decreased hospital admission rates for non-COVID-19 diseases in Denmark since the first lockdown. 2. Mortality rates were also shown to be higher for non-COVID-19 diseases, including respiratory diseases, cancer, pneumonia, and sepsis. Evidence Rating Level: 2 (Good) Study Rundown: The COVID-19 pandemic has put a...
1. Therapeutic anticoagulation with rivaroxaban or enoxaparin did not improve clinical outcomes and increased bleeding compared with prophylactic anticoagulation. 2. Net clinical benefit composite of death, thrombotic events, and major or clinically relevant non-major bleeding was not significantly different between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: COVID-19 is associated with...
1. Hospitalized COVID-19 patients receiving high-dose methylprednisolone followed by oral prednisone had improved clinical outcomes compared to patients receiving dexamethasone. Evidence Rating Level: 2 (Good) In June 2020, a preliminary report of a study was published comparing hospitalized COVID-19 patients receiving dexamethasone (DXM) 6 mg daily (for 10 days) to patients who...
1. A similar proportion of patients died within 28 days of randomization in both groups (high-titre convalescent plasma vs. usual care). 2. Allocation to convalescent plasma had no significant effect on the proportion of patients discharged from hospital within 28 days. Evidence Rating Level: 1 (Excellent) Study Rundown: Convalescent plasma is a...
1. In-hospital mortality within 30 days of admission for COVID-19 was 48% (vs. global mortality 31.5%). 2. Increased age, underlying comorbidities and delay in admission were associated with an increased mortality rate among African patients. Evidence Rating Level: 2 (Good) Study Rundown: The COVID-19 pandemic has exposed long-standing inequities in healthcare. Critically...