Tag: Coronavirus

1. Patients with COVID-19-related acute respiratory distress syndrome (ARDS) had a comparable 90-day mortality rate to those with non-COVID ARDS on extracorporeal membrane oxygenation (ECMO). 2. Higher patient age, higher PaO2:FiO2 ratio and presence of significant acute or chronic disease were all associated with greater risk of mortality in COVID-19...
1. Use of the novel molecular point-of-care testing, the QIAstat-Dx Respiratory SARS-CoV-2 Panel, was associated with a much shorter time to results compared to laboratory PCR testing. 2. Point-of-care testing demonstrated superior specificity and sensitivity to standard PHE RdRP and E gene assay for COVID-19. Evidence Rating Level: 2 (Good) Study Rundown:...
1. The proportion of out of hospital cardiac arrests (OHCAs) within all acute myocardial infarction (AMI) hospital admissions was higher at the start of the COVID-19 pandemic compared to before, by a difference of 2.0%. 2. The in-hospital mortality rate for OHCAs during COVID-19 was higher than before, by a...
1. Extracorporeal membrane oxygenation (ECMO) for COVID-19 related acute respiratory distress syndrome (ARDS) was associated with 60-day survival rates similar to other studies evaluating ECMO in severe ARDS. 2. ECMO in COVID-19 related ARDS was associated with an increased risk of pulmonary emboli despite thromboprophylaxis. Evidence Rating Level: 2 (Good) Study Rundown:...
1. The COVID-19 lockdown was associated with a significantly increased risk of preterm birth, institutional stillbirth and neonatal mortality in Nepal. 2. The overall number of institutional births were significantly reduced with national lockdown, with increased inequality noted across ethnicities. Evidence Rating Level: 2 (Good) Study Rundown: Modelling studies have estimated a...
1. There was no significantly increased risk of ICU admission, intubation, or death among hospitalized patients with COVID-19 and active malignancy compared with a matched cohort of patients with COVID-19 and no malignancy. Evidence Level Rating: 2 (Good) Some institutions in the U.S. have reported higher rates of COIVD-related complications and...
1. Pediatric patients during the COVID-19 pandemic present with a wide range of cardiac manifestations that require early detection and treatment. Evidence Rating Level: 2 (Good) The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has resulted in increased hyperinflammatory presentations in otherwise healthy children. This international, multi-center, retrospective chart...
1. Seroprevalence of SARS-CoV-2 antibodies was generally low in healthcare workers but higher than the general population. 2. Loss of taste or smell was most strongly associated with seropositivity in healthcare workers. Evidence Rating Level: 2 (Good) Study Rundown: Healthcare workers comprised a significant proportion of individuals who tested positive for...
1. Severe acute respiratory syndrome coronavirus 2 infection increases the rate of Kawasaki disease in children. 2. Individuals with severe Kawasaki disease were more likely to have myocarditis, require combination therapy with inotrope treatment, and require admission to the intensive care unit. Evidence Rating Level: 2 (Good) Study Rundown: Viral disease is...
1. Healthcare workers in the United States and United Kingdom had at least a three-fold greater risk of COVID-19 infection than the general public. 2. Black, Asian, and minority ethnic healthcare workers were at a disproportionately higher risk of SARS-CoV-2 infection, as were those re-using personal protective equipment or with...