2 Minute Medicine Rewind December 9, 2019
Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial 1. Obeticholic ...
Tag: human immunodeficiency virus (HIV)
The NAMSAL ANRS 12313 trial: HIV viral suppression similar for dolutegravir and low-dose efavirenz treatment
1. For previously untreated HIV-1 patients in Cameroon, treatment with dolutegravir was noninferior to low dose efavirenz at lowering viral ...
Quick Take: HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception
Previous studies have suggested that certain hormonal contraceptive methods, including intramuscular depot medroxyprogesterone acetate (DMPA-IM), may increase women’s susceptibility to ...
2 Minute Medicine Rewind June 17, 2019
Suicide in older adults living in or transitioning to residential long-term care, 2003 to 2015 It is estimated that by ...
Quick Take: Assessment of the Safety of Pembrolizumab in Patients With HIV and Advanced Cancer—A Phase 1 Study
Immunotherapies such as anti-PD-1 (anti-programmed cell death 1) and anti-PD-L1 (anti-programmed cell death ligand 1) are effective in treating numerous ...
2 Minute Medicine Rewind June 10, 2018
The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, ...
Quick Take: Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER)
Early evidence has suggested a strong association between HIV viral load and the risk of transmission to an HIV-negative partner, ...
Quick Take: Influence of HIV Infection on the Natural History of Hepatocellular Carcinoma: Results From a Global Multicohort Study
Hepatocellular carcinoma (HCC) is a rapidly increasing cause of morbidity and mortality in patients affected by HIV. However, the impact ...
Most commonly used HIV drug worldwide not associated with increased risk for suicide in Uganda
1. No baseline differences observed between patients exposed to efavirenz and nevirapine compared to those never exposed, regarding both depression ...
In-utero exposure to tenofovir-emtricitabine not associated with higher risk of adverse birth outcomes
1. Pairwise comparisons of tenofovir-emtricitabine and ritonavir-boosted lopinavir (TDF-FTC-LPV/r), zidovudine-lamivudine and ritonavir-boosted lopinavir (ZDV-3TC-LPV/r), and tenofovir-emtricitabine and ritonavir-boosted atazanavir (TDF-FTC-ATV/r) ...