#VisualAbstract: Oral Nirmatrelvir-Ritonavir Postexposure Prophylaxis Does Not Reduce the Risk of Developing Symptomatic Covid-19
Click here to read this study in the NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be ...
Tag: Prophylaxis
#VisualAbstract: Cyclophosphamide-tacrolimus-mycophenolate mofetil is an effective prophylaxis against graft-versus-host disease
1. In this randomized controlled trial, cyclophosphamide-tacrolimus-mycophenolate mofetil was associated with lower rates of graft-versus-host disease (GVHD) compared to ...
Azithromycin use is associated with reduced maternal sepsis in vaginal deliveries
1. In this randomized controlled trial, a single dose of azithromycin reduced the risk of maternal sepsis or death among ...
#VisualAbstract: A randomized trial of hydroxychloroquine as postexposure prophylaxis for COVID-19 did not show any benefit
1. In this double-blind, randomized trial, hydroxychloroquine did not reduce symptom severity in an adult, outpatient population. 2. More side ...
Candidate drug to prevent HIV infection in women safe and well-tolerated in phase 2 trial
1. Maraviroc pre-exposure prophylaxis regimens were observed to be safe and well tolerated in patients. 2. No new HIV infections ...
Community treatment of HIV pre-exposure prophylaxis demonstrated low acquisition rate but disparities in adherence
1. For patients who received pre-exposure prophylaxis delivered through sexual health clinics in the United States, the adherence rate was ...
High-dose prophylaxis for hemophilia increases costs with minimal benefit
Image: PD 1. High-dose prophylaxis for severe hemophilia increases total cost of care. 2. Compared to intermediate-doses, high-dose prophylaxis reduces bleeding ...
Short-term zinc prophylaxis decreases infant diarrhea morbidity
Image: PD 1. Short-term zinc prophylaxis in infants is associated with decreased morbidity from diarrheal episodes. 2. In those infants ...
2 Minute Medicine Rewind
In this section, we will highlight the some of the key high-impact studies, updates, and analyses published in the past ...