Tag: relapsing multiple sclerosis

1. This cohort study found that younger age, spinal cord involvement, and gadolinium-enhancing lesions on magnetic resonance imaging were associated with earlier onset of multiple sclerosis clinical disease in patients with radiologically isolated syndrome. 2. With the widespread use of magnetic resonance imaging technology, early recognition and stratification of associated...
1. The use of highly effective disease-modifying treatments for relapsing-remitting multiple sclerosis was significantly more prevalent in Swedish patients compared to Danish patients and was associated with significant reductions in the rate of confirmed disability worsening and relapse rates. 2. The findings demonstrated that differences in national treatment strategies and...
1. Hookworms was found to be a safe and well tolerated treatment option possibly associated with an immunobiological effect in relapsing multiple sclerosis. Evidence Rating Level: 2 (Good) Multiple sclerosis (MS), an immune-mediated central nervous system disease, is associated with an imbalance between inflammatory cytokines and immunoregulatory factors, namely regulatory T...
The association between use of proton-pump inhibitors and excess mortality after kidney transplantation: A cohort study 1. PPI use may be associated with an increased mortality risk in patients who have received kidney transplants. Evidence Rating Level: 1 (Excellent) Proton-pump inhibitors (PPIs) are commonly prescribed to kidney transplant recipients (KTRs) to protect...
Multiple sclerosis (MS) is a progressive, degenerative disease that damages myelin sheaths in the central nervous system. The RADIANCE phase 2 study previously established that ozanimod, a sphingosine 1-phosphate receptor modulator, demonstrates greater efficacy on MRI measures in patients with relapsing MS. SUNBEAM, a randomized, double-dummy, double-blind, active-controlled phase...
Prehospital Stroke Management Optimized by Use of Clinical Scoring vs Mobile Stroke Unit for Triage of Patients with Stroke: A Randomized Clinical Trial The effective management of intracranial hemorrhage (ICH) or large-vessel occlusion (LVO) requires effective triaging to hospitals with appropriate treatment capabilities, ranging from comprehensive stroke centers (CSC) to...