Tag: stem cell

Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study 1. NIRS imaging in patients undergoing cardiac catheterization for suspected coronary artery disease can be used in identifying high-risk non-culprit lesions contributing to future major adverse coronary events.  Evidence Rating Level:...
Umbilical cord blood (UCB) is a rich source of stem cells for transplantation in patients with hematologic malignancies. However, its widespread utilization has been limited by the generally slow rate of hematopoietic recovery. In a first-in-human pilot study of an ex-vivo expanded UCB product (NiCord) used in combination with...
Apixaban to Prevent Venous Thromboembolism in Patients with Cancer The risk of venous thromboembolism (VTE) is significantly increased in patients with active cancer. While parenteral prophylactic anticoagulation has been shown to reduce the risk of VTE in cancer patients, its use is associated with an increased risk of major bleeding...
  1. Following treatment with glucocorticoids, human hematopoietic stem cells (HSCs) from cord blood demonstrated enhanced homing and engraftment to bone marrow in mice. 2. Glucocorticoids improved HSC homing by increasing histone acetylation, which resulted in increased CXCR4 expression. Evidence Rating Level: 2 (Good) Study Rundown: HSCs from cord blood are used for...