Tag: transfusion

1. Prehospital plasma transfusion is associated with increased survival in the setting of hemorrhagic shock, particularly with longer transport times Evidence Rating Level: 1 (Excellent) It has been well established that the early transfusion of blood products in the setting of hemorrhagic shock reduces associated morbidity and mortality. Only recently, however,...
1. The authors observed in this retrospective cohort study that transfusion rates decreased among patients from 2010 and 2014. 2. Paralleling decreasing transfusion rates, the authors observed a reduction in 6-month mortality rates among patients with moderate anemia from 2010 and 2014. Evidence Rating Level: 2 (Good) Study Rundown: Anemia is a...
1. In this retrospective analysis, there was a slight increase in male patient mortality per transfusion when receiving blood from an ever-pregnant donor compared to a male or never-pregnant female donor. 2. This association seemed to be strongest for recipients under 50 years of age. Evidence Rating Level: 3 (Average) Study Rundown:...
  Dry Care Versus Antiseptics for Umbilical Cord Care: A Cluster Randomized Trial Because omphalitis is rare in developed countries, the benefit of antiseptic use in umbilical cord care have not been shown. The purpose of this study was to assess the noninferiority of dry care compared with antiseptics in France...
1. Perioperative transfusion for gastric cancer resection was linked to a decrease in recurrence-free survival by 66%. 2. Regardless of timing, number of units, or stage of disease, transfusion was linked to a decrease in recurrence-free survival (RFS) and overall survival (OS) in gastric cancer patients. Evidence Rating Level: 2 (Good)          Study...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Age of Transfused Blood in Critically Ill Adults Whether the administration of fresh red blood cells instead of red blood cells that have been stored for a period of time improves outcomes...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Effect of a Balloon-Expandable Intracranial Stent vs Medical Therapy on Risk of Stroke in Patients With Symptomatic Intracranial Stenosis Intracranial stenosis is a common etiology of stroke, often treated with percutaneous...
1. For post-cardiac surgery patients, a restrictive transfusion threshold was not superior to a liberal transfusion threshold in terms of major infection and ischemic events at 3 months. 2. More deaths occurred in the restrictive threshold group than the liberal threshold group. 3. No significant differences in total cost was found...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women Pre-exposure prophylaxis with tenofovir combined with or without emtricitabine has been shown to significantly reduce rates of HIV acquisition in populations including men...
1. Large volume transfusion requirement and mortality in trauma are better predicted using clot lysis velocity curves. 2. Pathological hyperfibrinolysis can be predicted earlier in trauma using the maximum rate of lysis (MRL) which may facilitate earlier decision making at no additional cost. Evidence Rating Level: 2 (Good) Study Rundown: In acute...