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Guselkumab (Tremfya) strengthens its case for protecting joints in psoriatic arthritis
1. The FDA has expanded the label for guselkumab (Tremfya) to include evidence that it can inhibit progression of structural...
Rheumatology
Physical therapy yields modest improvements in chronic low back pain
1. In this randomized controlled trial, physical therapy (PT) was associated with a modest improvement in function compared with cognitive...
Infrapatellar fat pad glucocorticoid injections may not reduce pain or effusion volume in patients with knee osteoarthritis
1. Infrapatellar fat pad (IPFP) glucocorticoid injections do not significantly reduce pain or effusion volume compared to placebo in knee...
Tofacitinib may improve patient-reported outcomes in juvenile idiopathic arthritis
1. Tofacitinib significantly improves patient-reported outcomes compared to placebo in the management of juvenile idiopathic arthritis (JIA). Evidence Rating Level:...
C-reactive protein measurements may be misleading due to large within-person variability
1. Single C-reactive protein (CRP) measurements can be highly misleading due to large within-person variability, especially at higher values; repeat...
Increased gut inflammation is associated with greater structural spinal damage in axial spondyloarthritis
1. Increased gut inflammation, as measured by fecal calprotectin, is significantly associated with greater structural spinal damage in axial spondyloarthritis...
A digital psychological intervention is associated with improved psychological outcomes in patients with inflammatory rheumatic diseases
1. In patients with inflammatory rheumatic diseases (IRD), digital psychological intervention was associated with improved psychological outcomes and quality of...
Utility of long-term routine laboratory toxicity monitoring of immunomodulatory drugs in rheumatoid arthritis
1. In this retrospective cohort study involving patients with rheumatoid arthritis on disease-modifying antirheumatic drugs, long-term routine laboratory toxicity monitoring...
Medical cannabis has a high discontinuation rate for treatment of musculoskeletal pain
1. Medical cannabis has a high discontinuation rate among patients with chronic musculoskeletal pain, particularly in the first few months,...
Hydroxychloroquine may have a treatment role for chronic inflammatory cardiomyopathy
1. Hydroxychloroquine plus prednisolone reduced the 12-month risk of the composite cardiovascular outcome by 72 percent compared with prednisolone alone....
