• About
  • Masthead
  • License Content
  • Advertise
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

Sign in
SUBSCRIBE
  • About
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
    • Rewinds
    • The Scan
  • EvidencePulse™
  • HypeCheck™
  • AI News
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Tools
    • NPI Registry Lookup
    • RVU Search
  • Partners
    • License Content
    • Advertise with Us
2 Minute Medicine
  • About
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
    • Rewinds
    • The Scan
  • EvidencePulse™
  • HypeCheck™
  • AI News
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Tools
    • NPI Registry Lookup
    • RVU Search
  • Partners
    • License Content
    • Advertise with Us
Sign in
SUBSCRIBE
2 Minute Medicine
Sign in
Subscribe
✦ EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Ask the evidence.
Get the signal.
Try it now → Physician-trained medical AI by 2 Minute Medicine
Home All Specialties Chronic Disease

Cognitive-behavioural therapy alternating between face-to-face and online module sessions effective for treating anxiety disorders

byDavy LauandAlex Chan
November 15, 2021
in Chronic Disease, Psychiatry
Reading Time: 2 mins read
American Academy of Pediatrics recommends standards for adverse event disclosures
Share on FacebookShare on TwitterShare on LinkedIn

1. A blended model of CBT (bCBT), consisting of face-to-face sessions alternated with online module sessions, was as clinically effective for treating anxiety disorders as solely face-to-face CBT (ftfCBT)

2. bCBT was equally as acceptable to patients and therapists, and was more cost-effective than ftfCBT for direct medical costs.

Evidence Rating Level: 2 (Good)

Cognitive behavioural therapy (CBT) is an effective treatment for anxiety disorders. However, fewer than 50% of people with anxiety disorders undergo appropriate treatments, with reasons including lack of therapists and high therapy costs. A proposed alternative to mitigate costs and improve accessibility is Internet-delivered CBT (iCBT), which consists of online modules with and without an online therapist assisting. However, there is reluctance for therapists to use iCBT due to low adherence, concerns about addressing complex symptoms, and not being able to form strong interpersonal relationships. Therefore, a blended CBT (bCBT) approach has been proposed, combining iCBT with face-to-face CBT (ftfCBT): A feasibility randomized controlled trial was done with 18 participants randomized to either treatment, finding no difference between these groups in reduction of anxiety symptoms. The current randomized controlled trial aimed to investigate the acceptability, cost-effectiveness, and clinical effectiveness of bCBT compared to ftfCBT, for patients with panic disorder (PD), social anxiety disorder (SAD), and generalized anxiety disorder (GAD) in outpatient care. In total, there were 52 patients randomized to bCBT and 62 to ftfCBT, with a mean (SD) age of 36.3 (10.6). The bCBT group received 15 weekly sessions alternating between face-to-face and online modules with asynchronous feedback from the therapist. Questionnaires at baseline, week 7 (mid-treatment), week 15 (post-treatment), and 1 year follow-up were used to assess the outcomes of acceptability (such as treatment adherence, treatment preference, and satisfaction) and clinical effectiveness (using the Beck Anxiety Inventory (BAI)). The results showed that adherence was not significantly different between the groups, with bCBT being slightly higher (67.4% versus 61.6% completing all sessions, p = 0.608). There was also no difference in ratings of the therapeutic alliance, using the Working Alliance Inventory (WAI-SR), from both the patients’ (p = 0.912) and therapists’ perspectives (p = 0.762). Treatment satisfaction was also not different (p = 0.750), with the mean Client Satisfaction Questionnaire (CSQ-8) scores for both falling between “somewhat satisfied” and “very satisfied”. Furthermore, there were no significant differences in BAI score, representing decreased anxiety severity, between the two groups post-treatment and at 1-year follow-up (p = 0.477 and 0.093 respectively). In terms of cost-effectiveness, bCBT was significantly cheaper for direct medical costs, which were €3758 for bCBT and €3841 for ftfCBT during the 1-year period (mean difference -83.78, 95% CI -96.96 to -70.61, p < 0.001). For societal costs, which included medical, patient, and productivity costs, were not different between the two treatments (€10,945 for bCBT, €10,937 for ftfCBT, mean difference 26.46, 95% CI -24.64 to 42.71, p > 0.01). Overall, this study demonstrated that bCBT is as clinically effective as ftfCBT for anxiety disorders, and is equally acceptable to patients and therapists while being more cost-effective in terms of direct medical costs. However, further randomized trials with greater sample sizes will be needed to strengthen and validate these findings.

Click to read the study in PLOSONE

Image: PD

RELATED REPORTS

Children with intellectual and developmental disabilities have increased risks of depression and anxiety

Artificial intelligence (AI) chatbot reduced depression, anxiety, and eating disorder risk symptoms

©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: anxietyCBTdepressionpsychiatry
Previous Post

2 Minute Medicine Rewind November 15, 2021

Next Post

Maternal genetic risk of hypertension associated with reduced placental weight

RelatedReports

A young boy studying at a desk with books and a contrasting image of an adult man walking outdoors, symbolizing the life course from childhood to adulthood.
Pediatrics

Children with intellectual and developmental disabilities have increased risks of depression and anxiety

October 14, 2026
A man sits pensively by a window with a depiction of a synapse illustrating neurotransmitter activity, suggesting a focus on mental health treatment mechanisms.
Artificial Intelligence

Artificial intelligence (AI) chatbot reduced depression, anxiety, and eating disorder risk symptoms

September 11, 2026
A funnel containing papers, a laboratory sample container, a physician working on a laptop, and a clock in the background, suggesting automation in medical workflows.
Artificial Intelligence

Universal Health Services acquisition of Talkspace connects virtual and inpatient behavioral care

September 9, 2026
Sleep duration, sleepiness, chronotype have variable associations with teen self-regulation
Chronic Disease

Cognitive behaviour therapy may be superior to bright light therapy for insomnia in women with breast cancer undergoing chemotherapy

September 3, 2026
Next Post
USPSTF finds insufficient evidence for screening for iron deficiency anemia during pregnancy

Maternal genetic risk of hypertension associated with reduced placental weight

Combined MRI and NIH stroke scores may predict stroke prognosis

Deep brain stimulation may improve clinical outcomes in individuals with treatment resistant depression  

Patient Basics: Lung Cancer Overview

Adjuvant gefitinib compared to chemotherapy after lung cancer resection did not improve survival

✦ EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... Try EvidencePulse™ Get the signal. Try it now → Physician-trained medical AI by 2 Minute Medicine

2MM+ All Access

Full details →
$4.99 /month

3-day free trial · cancel anytime

  • ✓100+ physician-written reports
  • ✓EvidencePulse™ + HypeCheck™
  • ✓Ad-free reading + newsletters
Start 3-day free trial

Then $4.99/month. Manage renewal in your account.

NPI Lookup · Free

Look up any US clinician

Search by name or NPI number, live from the CMS NPI Registry.

  • OIG exclusion check
  • Licenses and specialties
  • No account needed
Open NPI Lookup →

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Children with autism spectrum disorder may have reduced fecal microbial diversity
  • Variable homicide mortality rates among women aged 15-44 years depending on state abortion policy
  • An artificial intelligence model demonstrates the potential for improving the efficiency of structural heart disease screening using electrocardiograms
License Content
Terms of Use | Disclaimer
Cookie Policy
2MM+ All Access Full details →

The medical literature, distilled daily.

Monthly plan selected: $4.99 /month.

$4.99/month

3-day free trial · cancel anytime

Start 3-day free trial

Then $4.99/month. Manage renewal in your account.

Yearly plan selected: $49.90 /year.

$49.90/year

2 months free

Start 3-day free trial

Then $49.90/year.

Membership benefits

  • ✓100+ physician-written reports
  • ✓AI EvidencePulse™ + HypeCheck™
  • ✓Ad-free reading + newsletters
  • ✓NPI watchlist + bulk NPI verification

Already a member? Sign in

  • About
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
    • Rewinds
    • The Scan
  • EvidencePulse™
  • HypeCheck™
  • AI News
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Tools
    • NPI Registry Lookup
    • RVU Search
  • Partners
    • License Content
    • Advertise with Us
No Result
View All Result

© 2026 2 Minute Medicine, Inc. - Physician-written medical news.