• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Ferric carboxymaltose comparable to oral iron supplementation for pregnant women with anemia

byNeel MistryandTeddy Guo
May 30, 2023
in Chronic Disease, Obstetrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Although anemia prevalence at 36 weeks was slightly lower in the ferric carboxymaltose group compared to standard-of-care, statistical significance was not achieved.

2. Adverse events between both groups were comparable; there were no changes in birth weight.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Anemia affects more than one-third of all pregnancies in Africa. Although oral iron supplementation is recommended during pregnancy, patient adherence and uptake may be unsatisfactory. Ferric carboxymaltose is an intravenous iron formulation that can be administered in a single dose as an alternative, however, current evidence regarding its effectiveness is limited. This randomized controlled trial aimed to compare the safety and efficacy of ferric carboxymaltose with oral iron supplementation for the treatment of anemia among Malawian pregnant women. The primary outcome was anemia at 36 weeks gestation while key safety outcomes included infusion-related adverse events and all adverse events up to 4 weeks post-partum. According to study results, ferric carboxymaltose did not significantly reduce anemia prevalence or increase birthweight compared to standard-of-care. This study was strengthened by a large sample size of women who were followed for several months. However, the results may have limited generalizability as its enrollment only included patients from Malawi.

Click to read the study in The Lancet

Relevant Reading: Benefits and Risks of Iron Interventions in Infants in Rural Bangladesh

RELATED REPORTS

Abbreviated MRI is superior to whole-breast ultrasound for detection of cancer in dense breasts

App-based physical activity intervention may have a limited role among women with prior hypertensive pregnancy disorder

The 2 Minute Medicine Podcast Episode 55

In-depth [randomized-controlled trial]: Between Nov 12, 2018, and Mar 2, 2021, 21 258 patients were screened for eligibility across 2 regions in Malawi, Africa. Included were women with capillary hemoglobin < 10.0 g/dL and negative malaria diagnostic test. Altogether, 862 patients (430 in ferric carboxymaltose and 432 in standard care) were included in the intention-to-treat analysis. Although anemia prevalence at 36 weeks’ gestation was lower in the ferric carboxymaltose group (52%) compared to standard-of-care (57%), statistical significance was only achieved at 4 weeks (prevalence ratio [PR] 0.91, 95% confidence interval [CI] 0.85-0.97). Furthermore, birthweight was comparable between groups (mean difference -3.1g, p=0.93). Most adverse events were mild-to-moderate in nature and comparable between groups (43% in ferric carboxymaltose vs. 39% in standard-of-care, risk ratio 1.08, p=0.34). There were no infusion-related adverse events. Overall, findings from this study suggest that ferric carboxymaltose did not reduce anemia prevalence at 36 weeks’ gestation among anemic pregnant women in Africa.

Image: PD

©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: anemiaferric carboxymaltoseiron deficiency anemiairon supplementationwomen's health
Previous Post

POT1-mediated long telomere syndrome is associated with familial clonal hematopoiesis

Next Post

Increased risk of mortality and epilepsy in individuals post-stroke

RelatedReports

3D mammography (tomosynthesis) enhances accuracy of breast cancer screening
Chronic Disease

Abbreviated MRI is superior to whole-breast ultrasound for detection of cancer in dense breasts

June 25, 2025
Prevalence of hypertension among adolescents varies by race and BMI
Cardiology

App-based physical activity intervention may have a limited role among women with prior hypertensive pregnancy disorder

April 11, 2025
The 2 Minute Medicine Podcast Episode 15
2MM Podcast

The 2 Minute Medicine Podcast Episode 55

April 5, 2025
Ticagrelor reversal agent provides immediate and sustained effect
Cardiology

Liberal transfusion may improve outcomes in myocardial infarction and anemia

October 1, 2024
Next Post
Patient Basics: Epilepsy

Increased risk of mortality and epilepsy in individuals post-stroke

Prevalence of hypertension among adolescents varies by race and BMI

Birth weight modifies association between weight and hypertension in childhood and adolescence

#VisualAbstract: Ketamine versus Electroconvulsive Therapy for Non-psychotic Treatment-Resistant Major Depression

#VisualAbstract: Ketamine versus Electroconvulsive Therapy for Non-psychotic Treatment-Resistant Major Depression

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Breast cancer survivors may have a lower risk of Alzheimer’s dementia
  • Evaluating scar outcomes in pediatric burn patients following skin grafting 
  • Novel inhibitory antibody, MAR001, lowers triglycerides and remnant cholesterol in humans
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.