• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Gut microbiota signatures of long-term and short-term plant-based dietary pattern and cardiometabolic health

byIshita AggarwalandAlex Chan
June 20, 2022
in Chronic Disease, Gastroenterology
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. Long-term plant-based diet was associated with more variance in microbial structure and future cardiometabolic biomarkers, suggesting a possible protective role

Evidence Rating Level: 2 (Good)

Plant-based dietary pattern is gaining increasingly more attention from both the scientific community and general public. Prior research suggests that plant-based foods are associated with lower risk of cardiometabolic diseases, such as obesity, cardiovascular disease, and type 2 diabetes, and lower risk of cardiovascular mortality. Gut microbiota provides a key connection between diet and metabolic health. It is unclear how plant-based dietary pattern may influence gut microbiota profiles. Hence, this study aimed to examine the associations of long-term habitual plant-based dietary pattern with gut microbiota profiles in a population-based prospective cohort study in China. A total of 3096 participants from 15 provinces across China were included. A healthful plant-based diet index (hPDI), unhealthful plant-based diet index (uPDI), and overall plant-based diet index (PDI) were created. The average PDIs were calculated using repeat food frequency questionnaires (FFQs) collected in 2011 and 2015, representing a long-term dietary pattern. In 2015, 3-day 24-hour dietary recalls were collected to estimate a short-term dietary pattern. Fecal samples were collected and measured using 16S rRNA sequencing. The association of long- and short-term plant-based dietary patterns with gut microbial diversity were investigated. There was a significant association between short-term hPDI and microbial alpha-diversity. Long-term plant-based diet was correlated with more variance in microbial overall structure. Only microbes related to long-term estimates showed association with future cardiometabolic biomarkers. These findings may offer insights into the protective role of long-term plant-based dietary pattern for cardiometabolic health.

Click here to read the study in BMC Medicine

Relevant Reading: Influence of diet on the gut microbiome and implications for human health

In-Depth [Prospective Cohort Study]: The present study was based on data from the China Health and Nutrition Survey (CHNS). To examine the relationship between the long-term plant-based dietary pattern and gut microbiome, 3096 adult participants who completed FFQs were included. To link short-term plant-based dietary pattern with gut microbiome, 3066 participants who completed 3-day 24-hour dietary recalls during stool sample collection were included. A hPDI, uPDI, and overall PDI were calculated based on 15 food groups. Healthy plant food groups included whole grains, fruits, vegetables, nuts, legumes, vegetable oils, and potatoes, while less healthy plant food groups included refined grains, beverages and fruit juices, and sweets and desserts. Animal food groups included eggs, meat, animal oils, dairy, and fish or seafood. Stool samples were used for microbial DNA extraction and paired-end 16S rRNA gene sequencing and subsequently, taxonomic and functional profiles were generated. Statistical analyses included linear regression. In 2015, the mean (± SD) PDI were 45 ± 5 and 46 ± 6 for long-term diet and short-term diet, respectively. Participants with a higher long-term or short-term PDI score were less likely to be smokers or alcohol drinkers. Long-term PDIs and all 15 constituent food groups were significantly correlated with corresponding short-term estimates (p < 0.05). The correlation coefficients were 0.26, 0.28, and 0.22 for PDI, hPDI, and uPDI, respectively. Higher short-term hPDI was associated with higher Shannon’s diversity index and Pielou’s measure of species evenness. However, no statistically significant association was seen between the long-term PDIs and microbial alpha-diversity. Furthermore, the association between long-term PDIs and microbial beta-diversity was stronger than short-term PDIs. Four gut microbial features (Shannon’s diversity index, observed features, Peilou’s measure of species unevenness, and Faith’s phylogenetic diversity) of long-term plant diet were significantly associated with future fasting cardiometabolic risk biomarkers, including fasting insulin, HDL-C, LDL-C, TG, and CRP. However, gut microbial features related to short-term dietary estimates showed no significant association with future cardiometabolic risk biomarkers. These results provide information regarding possible associations between diet-related gut microbial features and cardiometabolic health.

RELATED REPORTS

Mazdutide significantly reduces weight in adults with overweight or obesity

Oral vancomycin may be effective for pouchitis in inflammatory bowel disease

Structured exercise intervention improves survival in colon cancer patients

Image: PD

©2022 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: chronic diseaseGastroenterologynutrition
Previous Post

2 Minute Medicine Rewind June 20, 2022

Next Post

Sotrovimab reduces the severity of COVID-19 progression

RelatedReports

Increasing maternal BMI linked to higher risk of cerebral palsy
Cardiology

Mazdutide significantly reduces weight in adults with overweight or obesity

July 11, 2025
Biosimilar to infliximab shows equivalent safety and efficacy for treating Crohn’s disease
Chronic Disease

Oral vancomycin may be effective for pouchitis in inflammatory bowel disease

July 10, 2025
Development of a risk index for colorectal cancer screening
Gastroenterology

Structured exercise intervention improves survival in colon cancer patients

July 9, 2025
Biosimilar to infliximab shows equivalent safety and efficacy for treating Crohn’s disease
Chronic Disease

Fecal calprotectin is a useful marker for defining small bowel endoscopic remission in Crohn’s disease

July 7, 2025
Next Post
Mortality after trauma increasingly due to preexisting conditions

Sotrovimab reduces the severity of COVID-19 progression

Reduced HPV vaccine doses may be adequate

Human Papillomavirus self-sampling may be a culturally-sensitive alternative for Muslim women

Decreased expression of nasal ACE2 may be correlated with lower prevalence of COVID-19 in children

Religious communities may have played both beneficial and detrimental roles during the COVID-19 pandemic

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Living in a marginalized neighbourhood is associated with worse outcomes in patients with myocardial infarction
  • SGLT2 inhibitors may delay cognitive impairment in elderly patients with heart failure
  • Nerandomilast slows decline in FVC in idiopathic pulmonary fibrosis
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.