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EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Ask the evidence.
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Home All Specialties Chronic Disease

Nurse Practitioners and Physician Assistants can effectively manage chronic conditions, fill gaps in primary care

byCaitlyn HuiandDeepti Shroff
November 21, 2018
in Chronic Disease, Endocrinology, Public Health
Reading Time: 2 mins read
Prevalence of hypertension among adolescents varies by race and BMI
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1. In this study, no significant differences were seen in the diabetes outcomes of patients managed by nurse practitioners (NPs) or physician assistants (PAs) compared to patients managed by physician primary care providers (PCPs).

2. The results of the study indicated that chronic illnesses could be effectively managed by any of the three forms of PCPs.

Evidence Rating Level: 2 (Good)

Study Rundown: In addition to primary care physicians, NPs and PAs are trained to be able to manage chronic conditions, such as diabetes. The authors of this study aimed to examine all three PCPs to assess whether NPs and PAs could be a possible solution to workforce shortages. The authors specifically assessed intermediate diabetes outcomes among patients of these three PCPs. The study concluded that there were no significant differences in diabetes outcomes regardless of which PCP was responsible for care. As a result, the authors suggest that NPs and PAs could help fill gaps in primary care for managing chronic conditions. The limitations of this study included that the majority of patients in this study were male and may not be represent a more generalized population.

Click to read the study in Annals of Internal Medicine

Relevant Reading: The Roles of Primary Care PAs and NPs Caring for Older Adults with Diabetes

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In-Depth [cohort study]: The authors conducted a cohort study that utilized data from the U.S. Department of Veterans Affairs electronic health record. The study outcomes included hemoglobin A1c (HbA1c), systolic blood pressure (SBP) and low-density lipoprotein cholesterol (LDL-C) of patients with diabetes. A total of 368 481 patients with diabetes were included. The authors utilized hierarchical linear mixed and logistic regression models for data analysis. Generally, none of the differences were statistically significant between the three PCPs. For example, model-estimated differences in HbA1c compared to primary care physicians were -0.05% (95% CI, -0.07% to -0.02%) for NPs and 0.01% (CIs, -0.02% to 0.04%) for PAs. Furthermore, differences for SBP were 0.08mmHg (CI, -0.34 to 0.18 mmHg) for NPs and 0.02 mmHg (CI, -0.42 to 0.38 mmHg) for PAs. 

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©2018 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

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