Renin-angiotensin-aldosterone system inhibitors do not affect COVID-19 risk
1. Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) were not shown to affect the risk of COVID-19. 2. ACE inhibitors ...
Tag: ACE inhibitors
Retracted: Underlying cardiovascular disease associated with increased mortality in COVID-19 patients
This article has since been retracted by NEJM on 6/11/2020. This 2MM article summary is left unchanged for historical context. ...
2 Minute Medicine Rewind May 4, 2020
Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial 1. Adults with severe COVID-19 treated with remdesivir ...
Renin-angiotensin system inhibition following transcatheter aortic valve replacement linked with lower cardiac mortality
1. Use of medications to inhibit the renin-angiotensin system (RAS) following transcatheter aortic valve replacement (TAVR) for severe aortic stenosis ...
The CREOLE trial: amlodipine and either hydrochlorothiazide or perindopril optimally lowers blood pressure in black African patients
1. Black African patients with hypertension randomized to multiple two-drug combinations experienced greater blood pressure control when treated with amlodipine ...
Pre-injury ACE inhibitors may reduce organ failure in obese trauma patients
1. Obese trauma patients receiving ACEi/ARB therapy pre-injury had reduced leukocyte inflammatory markers including DL1, CD328, CD154 and CD47 and ...
![Combo angiotensin-neprilysin inhibitor superior to enalapril in heart failure [PARADIGM-HF trial]](https://www.2minutemedicine.com/wp-content/uploads/2014/09/Angiotensin-350x250.jpg)
Combo angiotensin-neprilysin inhibitor superior to enalapril in heart failure [PARADIGM-HF trial]
1. LCZ696 is a novel drug that combines the neprilysin inhibitor, sacubitril, and the angiotensin receptor blocker (ARB), valsartan. 2. ...
ACE inhibitors associated with decreased mortality in diabetics
Image: PD 1. ACE-Inhibitors were significantly associated with decreased risk of all-cause mortality, cardiovascular death, myocardial infarction, and heart failure ...
The ATLAS trial: ACE inhibitor dosing in chronic heart failure [Classics Series]
Image: PD 1. When compared to a lower dose, high-dose angiotensin-converting-enzyme inhibitor significantly reduced the risk of hospitalization or death ...
The ACCOMPLISH trial: ACE inhibitors and calcium channel blockers for hypertension [Classics Series]
1. Benazepril plus amlodipine offers the same effect at reducing blood pressure in hypertensive patients as benazepril plus hydrochlorothiazide. 2. ...
