Tag: atrial fibrillation

1. The incidence of major bleeding events up to 8 weeks after catheter-directed atrial fibrillation ablation was significantly lower in those receiving continuous therapy with dabigatran compared to those receiving INR-directed warfarin. 2. Both groups experienced similar incidence of minor bleeding events and thromboembolic events. Evidence Rating Level: 1 (Excellent) Study Rundown:...
1. In patients with atrial fibrillation (AF) who undergo percutaneous coronary intervention (PCI), treatment with rivaroxaban, in addition to dual antiplatelet therapy (DAPT), led to significantly lower rates of clinically significant bleeding compared to treatment with DAPT and dose-adjusted vitamin K antagonist. 2. There were no significant differences between the...
1. Based on a retrospective cohort study of US Medicare patients, rivaroxaban was associated with a significantly increased risk of intracranial and extracranial hemorrhage compared with dabigatran when used in elderly patients with nonvalvular atrial fibrillation for stroke prevention. 2. There was a trend towards a decrease in thromboembolic stroke...
1. In patients with atrial fibrillation who were unable to receive warfarin for any reason, the use of apixaban reduced the risk of stroke and systemic embolism when compared to aspirin. 2. There were no significant differences between the groups in the risk of major bleeding. Original Date of Publication: March...
  Rate Control versus Rhythm Control for Atrial Fibrillation after Cardiac Surgery Atrial fibrillation, the most common post-operative complication of cardiac surgery, results in an increased risk for hospitalizations and other adverse events including death. This randomized trial conducted at 23 sites in the US and Canada enrolled 2,109 patients scheduled...
1. In this randomized controlled trial, there was no difference in total length of hospital stay after elective cardiac surgery in patients with postoperative atrial fibrillation randomized to either rhythm or rate control. 2. The secondary outcomes of death and adverse events also did not show any significant difference. Evidence Rating...
  Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies The cause of peripartum cardiomyopathy remains unknown and it has been hypothesized in the literature that it may have a significant genetic component. It shares many clinical similarities to idiopathic dilated cardiomyopathy. Using this association, the authors of this paper sequenced 43...
1. Patients with atrial fibrillation are at higher risk of ischemic stroke and systemic embolism. 2. Compared to placebo, warfarin and aspirin significantly reduced the risk of ischemic stroke and systemic embolism in patients with atrial fibrillation. 3. Today, antithrombotic therapy remains a vital consideration in managing patients with atrial fibrillation,...
1. Patients with atrial fibrillation are often treated with long-term oral anticoagulation, and may require interruption of their anticoagulation for elective surgeries or invasive procedures. 2. This study demonstrated that periprocedural bridging with dalteparin did not significantly reduce the risk of arterial thromboembolic disease when compared to placebo. 3. Patients treated...
Longitudinal evaluation of physician payment reform and team-based care for chronic disease management and prevention Primary care has an important economic impact on the health care system. Different models exist each with their own advantages and disadvantages on costs and health outcomes. Using population-based administrative data, the authors evaluated team-based...