Tag: coronary heart disease

1. Over 45% of deaths due to heart disease, stroke, and type 2 diabetes in US adults in 2012 was due to suboptimal dietary consumption. 2. The largest numbers of diet-related deaths were related to high sodium intake, low nuts/seeds, and high processed meats. Evidence Rating Level: 2 (Good) Study Rundown: Dietary...

1. In the 1970s, observational data suggested a direct link between serum cholesterol levels and the risk of coronary heart disease (CHD). 2. This trial was one of the first large, randomized studies to demonstrate that reducing lipid levels with cholestyramine could significantly lower death from CHD and nonfatal myocardial...

1. Night shift work was associated with a modestly increased risk of coronary heart disease in the Nurses' Health Study and Nurses' Health Study II. 2. Duration of night shift work was positively correlated with risk of incident coronary heart disease. Evidence Rating Level: 1 (Excellent)       Study Rundown:...

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. A Randomized Trial of Icatibant in ACE-Inhibitor-Induced Angiodema Bradykinin inhibitors such as icatibant are used in the treatment of hereditary angioedema, and they may also be effective for ACE-inhibitor-induced angioedema resulting in...

1. Improvement of population risk factors and increase of hyperlipidemia and hypertension treatment helped in part to prevent or postpone 38,000 deaths due to Coronary Heart Disease in the United Kingdom between 2000 and 2007. 2. Population-wide decreases in blood pressure and cholesterol levels, not attributable to medication use, had...

Image: PD 1. During a median follow-up of 3.7 years, there was no difference in the occurrence of the primary end point (a composite of cardiovascular death, myocardial infarction, and stroke) among medically-optimized stable coronary heart disease patients randomized to a darapladib or placebo.  2. Significantly more patients in the darapladib...

 Image: PD 1. An increased risk of coronary heart disease was found women with a history of renal stones. 2. The same association was not demonstrated in men with similarly adjusted variables. Evidence Rating Level:  2 (Good) Study Rundown: Nephrolithiasis is a common disease with increasing prevalence. Its relation to other systemic diseases,...